Naslov
In vitro susceptibility to antibiotics of Escherichia coli isolates in community acquired urinary tract infections

Autori
Barišić, Zvonimir ; Babić-Erceg, Andrea ; Borzić, Elmica ; Carev, Merica ; Kaliterna, Vanja ; Zoranić, Vinko ; Smoljanović, Mladen

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo

Izvornik
Clin Microbiol Infect / - , 2000, 97-98

Skup
10th European Congress of Clinical Microbiology and Infection

Mjesto i datum
Stockholm, Švedska, 28.05.2000. - 31.05.2000

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Escherichia coli ; antibiotics

Sažetak
Objectives: To determine in vitro susceptibility of E. coli isolates in community acquired urinary tract infections (CA-UTI) and to suggest optimal empirical antibiotic therapy in these patients. Methods: Three hundred fifthy seven consecutive strains of E. coli isolated from patients with CA-UTI were included in this study. Isolation and identification were performed by standard method and susceptibillity testing was performed by disk diffusion method. Susceptibillity was tested to amoxycillin (AMX), amoxycillin-clavulanate (AMC), cephalexin (CN), cefuroxime (CXM), ceftibuten (CTB), trimethoprim-sulfamethoxazole (STX) and ciprofloxacin (CIP). Results: From total number of 357 strains of E. coli 44.32% were resistant to AMX, 3.92% to AMC, 4.76% to CN, 2.24% to CXM, 0.84% to CTB, 17.09% to STX and 1.77% strains were resistant to ClP. Conclusions: The best in vitro susceptibillity was shown for ceftibuten, followed by ciproftoxacin and cefuroxime. Strains of E. coli show high resistance rate to trimethoprim-sulfamethoxazole and amoxycillin. The antibiotic of the best choice for empirical antibiotic therapy in patients with CA-UTI in our region is ceftibuten. Drugs like trimethaprim-sulphametoxazol or amoxycillin, most often prescribed in empirical therapy of CA-UTI, are not a good choice, because strains of E. coli show high rate of in vitro resistance to these antibiotics.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti, Javno zdravstvo i zdravstvena zaštita

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