Naslov
Effect of the linker length and amide group orientation on chiral bpa complexes of Zn(II) and Cu(II)

Autori
Pantalon Juraj, Natalija ; Moreth, Domonik ; Vianello, Robert ; Schatzschneider, Ulrich ; Kirin, Srećko I.

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
XIII Meeting of Young Chemical Engineers : Book of Abstracts / - , 2020, 176-176

ISBN
978-953-6894-71-0

Skup
XIII. susret mladih kemijskih inženjera (SMLKI 2020)

Mjesto i datum
Zagreb, Hrvatska, 20.02.2020. - 21.02.2020

Vrsta sudjelovanja
Poster

Vrsta recenzije
Nije recenziran

Ključne riječi
tridentate ligands ; hydrogen bonds ; geometrical isomers

Sažetak
Bis(2-picolyl)amine (bpa) and its derivatives are tridentate ligands known for the formation of complexes with late transition metals that found use as enzyme mimics, metal ion sensors and anticancer agents. In the Cambridge Structural Database, a variety of bpa complexes are described, such as monomers, dimers and coordination polymers. In this work, six chiral bpa ligands and their complexes with Zn(II) and Cu(II) were prepared and characterized by NMR, UV-Vis and CD spectroscopy. The stoichiometry, stereochemistry and possibility of different hydrogen bonding patterns were studied by DFT calculations. To optimize the formation of ML2 complexes, several variations were introduced into the ligand structure, such as the length of the CH2 linker, orientation of the amide group (-CO-NH- or -NH-CO-) and different chiral substituents. In ML2 complexes, the ligands have the possibility of forming one or two intramolecular hydrogen bonds. In these hydrogen bonded secondary structures, transfer of chirality by ''backdoor induction'' to the metal centre is possible and such complexes could selectively catalyse enantioselective reactions.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

Napomena
MZO-DAAD

POVEZANOST RADA