Naslov
SOX2 expression shifts during fetal development in the human prefrontal cortex

Autori
Kopić, Janja ; Đikić, Domagoj ; Krsnik, Željka

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
RECOOP 14th Bridges in Life Sciences and 2nd RECOOP-KFSD International Student Conference 2019 Abstract Book / - , 2019

Skup
2nd RECOOP – KFSD Student Conference

Mjesto i datum
Bratislava, Slovačka, 11.04.2019

Vrsta sudjelovanja
Poster

Vrsta recenzije
Podatak o recenziji nije dostupan

Ključne riječi
brain development ; proliferative zones

Sažetak
Cerebral cortex is a result of histogenetic processes, i.e. proliferation, migration, differentiation, specifications and synaptogenesis, regulated by differential gene expression. Proliferation occurs in the proliferative zones from neural stem cells. Neurons migrate from the proliferative zones to their final destination forming transient lamination:ventricular (VZ), subventricular (SVZ), intermediate (IZ), subplate (SP), cortical plate (CP) and marginal zone (MZ). Gene SOX2 encodes the transcription factor critically involved in cortical development, i.e. maintaining the identity of neural stem cells. However, SOX2 expression pattern during the human neocortical development remains elusive.

Izvorni jezik
Engleski

POVEZANOST RADA