Naslov
Agresivni oblik uznapredovalog takayasuova arteritisa u dojenačkoj dobi: prikaz slučaja
(Aggressive Progression of Takayasu’s Arteritis in Infancy: A Case Report)

Autori
Pavić, Roman ; Blažeković, Robert ; Divković, Dalibor ; Marjanović, Ksenija ; Sipl, Mirna

Izvornik
Acta clinica Croatica (0353-9466) 58 (2019), 3; 535-539

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, stručni

Ključne riječi
Takayasuov arteritis ; Dojenče ; Tromboza ; Imunosupresivna sredstva ; Prikazi slučaja
(Takayasu arteritis, Infant, Thrombosis, Immunosuppressive agents, Case reports)

Sažetak
Takayasu’s arteritis (TA) affects the aorta and its branches. Immunosuppressants are the usual course of therapy, while surgery has been used in acute cases. There is only scant information on TA in infancy, and the nonspecific symptoms in the initial stage of the disease make the diagnosis difficult and delayed, thus increasing the mortality rate. We describe a case of aggressive progression of TA in an infant. This child was the youngest to be affected with the disease as reported in the literature. A 3.5- month-old boy presented with cyanosis of both legs, tachycardia and antithrombin III deficiency. Computed tomography angiography (CTA) revealed thrombosis of distal aorta and both iliac arteries. Thrombectomy was performed at the level of both common femoral arteries. In addition, thigh amputation of the left leg had to be performed. TA was diagnosed postmortem with thrombosis of the distal aorta, its branches and upper mesenteric artery which was not occluded on previous CTA, glomerulonephritis and pulmonary parenchymal granulomatous infiltrations.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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