Naslov
Anhedonia in schizophrenia: mini-review

Autori
Šagud, Marina ; Šimunović Filipčić, Ivona ; Jakšić, Nenad ; Šimunić, Lucija ; Jezernik, Dejana ; Tudor, Lucija ; Madžarac, Zoran ; Stefanović, Ivana ; Kosanović Rajačić, Biljana ; Mihaljević-Peleš, Alma ; Vuksan-Ćusa, Bjanka ; Kudlek Mikulić, Suzan ; Pivac, Nela

Izvornik
Psychiatria Danubina (0353-5053) 31 (2019), Suppl 2; 143-147

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
anhedonia ; schizophrenia ; negative symptoms ; suicidality

Sažetak
The perception of reward exerts a powerful influence on human behavior. While anhedonia might occur in healthy individuals, its prevalence and severity are much higher in psychiatric patients, particularly those with depression and schizophrenia. Anhedonia is a negative symptom, and presumably a trait marker in schizophrenia. Recent research confirmed that anhedonia is a complex construct, consisting of anticipatory, consummatory, and reward learning components. In general, schizophrenia patients show anticipation deficits, and a substantial portion of them have physical (PA) and social anhedonia (SA). The relationship between anhedonia and psychopathology appears bidirectional. While gene-environment interactions affect reward circuity, anhedonia modulates clinical features, such as suicidality and nicotine consumption. Future clinical research employing longitudinal designs may shed more light on the dynamics and treatment of anhedonia in schizophrenia.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

POVEZANOST RADA