Naslov
Treatment options for pediatric psoriasis

Autori
Madiraca, Dora ; Šitum, Mirna ; Prkačin, Ivana ; Ožanić Bulić, Suzana

Izvornik
Acta dermatovenerologica Croatica (1330-027X) 24 (2016), 3; 175-180

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
pediatric psoriasis ; topical treatment ; systemic treatment ; biologic agents
(pedijatrijska psorijaza, topička terapija, sustavna terapija, biološka terapija)

Sažetak
ABSTRACT Psoriasis is a multifactorial inflammatory papulosquamous disease affecting 0.5% to 2% of the pediatric population. Pediatric pso-riasis, presenting similar to adult psoriasis, significantly reduces patient quality of life, often requiring an individualized treatment approach for each patient. Combination and rotational therapy are helpful in reduc-ing toxicity and maximizing efficacy. Patients with mild and limited dis-ease severity respond well to topical treatment with steroids or vitamin D analogues, unlike moderate and severe psoriasis where sufficient remission is rarely achieved. Therefore phototherapy, systemic immu-nomodulators, or biologic agents are the next line of treatment to be considered. There is limited data available on the use and long-term safety of biologics in the pediatric population. Biologic agents must be administered by experienced dermatologists, only in patients with moderate-to-severe plaque psoriasis who are intolerant or refractory to other systemic conventional disease-modifying treatment or photo-therapy, or if those treatments are contraindicated.

Izvorni jezik
Engleski

POVEZANOST RADA