Naslov
Impairment of cognitive and psychomotor performance in patients with inflammatory bowel disease

Autori
Zivkovic, Piero Marin ; Tadin Hadjina, Ivana ; Vilovic, Marino ; Rusic, Doris ; Tonkic, Ante ; Puljiz, Zeljko ; Bozic, Josko

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Tailored Therapies for IBD: A Look into the Future - Abstracts / - , 2018

Skup
Tailored Therapies for IBD: A Look into the Future

Mjesto i datum
Milano, Italija, 05.10.2018. - 06.10.2018

Vrsta sudjelovanja
Poster

Vrsta recenzije
Podatak o recenziji nije dostupan

Ključne riječi
cognitive and psychomotor performance, inflammatory bowel disease

Sažetak
Introduction: Patients with chronic diseases often experience cognitive deficits. Several risk factors for developing cognitive and psychomotor impairment are identified in patients with inflammatory bowel diseases (IBD). Although there is a growing evidence that cognitive impairments are found in different chronic illnesses, there is a limited research concerning IBD patients. Therefore, the aim of this study was to investigate cognitive and psychomotor performance in IBD patients and compare it to healthy controls. Methods: This study included 60 patients with IBD (30 Crohn’s disease and 30 ulcerative colitis) and compared them with age/gender matched controls. Participants were tested on three different tests of cognitive and psychomotor performance measuring reaction times of light stimulus perception, solving simple arithmetic operations, and complex psychomotor limb coordination using the computer-based system Complex Reactionmeter Drenovac (CRD-series). Three parameters were analysed ; total test solving time (TTST), minimum single task solving time (MinT) and total number of errors during test (TE). TTST and MinT were descriptors of speed, accuracy and mental endurance, while TE was a descriptor of attention and alertness. Results: In light signal position discrimination test (CRD311) patients with IBD had significantly longer TTST (36.75±6.5 vs. 33.28±7.5 s ; P=0.008) and MinT (0.46±0.08 vs. 0.41±0.08 s ; P=0.002), while there was no difference in TE (P=0.991). Patients with IBD had significantly longer TTST (151.40±62.90 vs. 122.78±38.46 s ; P=0.003) and MinT (2.33±0.72 vs. 1.96±0.55 s ; P=0.002) in simple arithmetic test (CRD11), while there was no difference in TE (P=0.318). In complex motor coordination test (CRD411) patients with IBD had significantly longer TTST (48.99±19.64 vs. 37.49±11.29 s ; P<0.001) and MinT (0.58±0.15 vs. 0.51±0.12 s ; P=0.006) and higher TE (12±9 vs. 7±5 ; P<0.001). Discussion / Conclusion: Results of this study indicate that patients with IBD have impaired cognitive and psychomotor performance when compared to healthy controls. Further research is needed to clarify the significance of these findings.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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