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Pregled bibliografske jedinice broj: 1031877

In vitro antioxidant and antihypertensive compounds from camu-camu (Myrciaria dubia McVaugh, Myrtaceae) seed coat: a multivariate structure-activity study

Fidelis, Marina; Santos, Jânio Sousa; Escher, Graziela Bragueto; Vieira do Carmo, Mariana; Azevedo, Luciana; Cristina da Silva, Marcia; Putnik, Predrag; Granato, Daniel
In vitro antioxidant and antihypertensive compounds from camu-camu (Myrciaria dubia McVaugh, Myrtaceae) seed coat: a multivariate structure-activity study // Food and chemical toxicology, 120 (2018), 479-490 doi:10.1016/j.fct.2018.07.043 (međunarodna recenzija, članak, znanstveni)

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Naslov
In vitro antioxidant and antihypertensive compounds from camu-camu (Myrciaria dubia McVaugh, Myrtaceae) seed coat: a multivariate structure-activity study

Autori
Fidelis, Marina ; Santos, Jânio Sousa ; Escher, Graziela Bragueto ; Vieira do Carmo, Mariana ; Azevedo, Luciana ; Cristina da Silva, Marcia ; Putnik, Predrag ; Granato, Daniel

Izvornik
Food and chemical toxicology (0278-6915) 120 (2018); 479-490

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
inhibition of lipid oxidation DPPH ; phenolic acids ; flavonoids ; food waste ; HPLC-DAD

Sažetak
Camu-camu (Myrciaria dubia) pulp, seeds, and skin are widely known because of their nutritional properties. However, the seed coat has never been studied as a source of bioactive compounds. Herein, we characterized the phenolic composition, the antioxidant activity, and inhibition of angiotensin-converting enzyme (ACE) of three different extracts (water, propanone, and ethanol) from this residue and assessed the structure-activity using bivariate and multivariate statistical approaches. Phenolic acids and flavonoids were quantified by high-performance liquid chromatography while the ferric reducing antioxidant power (FRAP), inhibition of lipid peroxidation using egg yolk and Wistar rat brain, scavenging of 2, 2-diphenyl-1-picrylhydrazyl (DPPH•) radical, Folin-Ciocalteu reducing capacity (FCRC), and the inhibition of angiotensin-converting enzyme (ACE) by the extracts were also analyzed. t-Resveratrol was found in camu-camu seed coat for the first time. The aqueous extract had the highest total phenolic content, FRAP, DPPH•, FCRC, and inhibition of lipid oxidation using both chemical and biological assays, while the propanone extract showed the opposite behavior but it presented higher in vitro antihypertensive activity. The ethanolic extract exhibited intermediate values for the responses. The association between chemical composition and the functional properties of the camu-camu seed coat extracts were revealed using correlation analysis and principal component analysis.

Izvorni jezik
Engleski

Znanstvena područja
Prehrambena tehnologija



POVEZANOST RADA

Projekti:
HRZZ-IP-2016-06-1913 - Ekstrakcije bioaktivnih spojeva iz mediteranskog bilja sa “zelenim otapalima” primjenom visokonaponskog pražnjenja (GREENVOLTEX) (Režek Jambrak, Anet, HRZZ - 2016-06) ( CroRIS)

Ustanove:
Prehrambeno-biotehnološki fakultet, Zagreb

Profili:

Avatar Url Predrag Putnik (autor)

Poveznice na cjeloviti tekst rada:

doi www.sciencedirect.com

Citiraj ovu publikaciju:

Fidelis, Marina; Santos, Jânio Sousa; Escher, Graziela Bragueto; Vieira do Carmo, Mariana; Azevedo, Luciana; Cristina da Silva, Marcia; Putnik, Predrag; Granato, Daniel
In vitro antioxidant and antihypertensive compounds from camu-camu (Myrciaria dubia McVaugh, Myrtaceae) seed coat: a multivariate structure-activity study // Food and chemical toxicology, 120 (2018), 479-490 doi:10.1016/j.fct.2018.07.043 (međunarodna recenzija, članak, znanstveni)
Fidelis, M., Santos, J., Escher, G., Vieira do Carmo, M., Azevedo, L., Cristina da Silva, M., Putnik, P. & Granato, D. (2018) In vitro antioxidant and antihypertensive compounds from camu-camu (Myrciaria dubia McVaugh, Myrtaceae) seed coat: a multivariate structure-activity study. Food and chemical toxicology, 120, 479-490 doi:10.1016/j.fct.2018.07.043.
@article{article, author = {Fidelis, Marina and Santos, J\^{a}nio Sousa and Escher, Graziela Bragueto and Vieira do Carmo, Mariana and Azevedo, Luciana and Cristina da Silva, Marcia and Putnik, Predrag and Granato, Daniel}, year = {2018}, pages = {479-490}, DOI = {10.1016/j.fct.2018.07.043}, keywords = {inhibition of lipid oxidation DPPH, phenolic acids, flavonoids, food waste, HPLC-DAD}, journal = {Food and chemical toxicology}, doi = {10.1016/j.fct.2018.07.043}, volume = {120}, issn = {0278-6915}, title = {In vitro antioxidant and antihypertensive compounds from camu-camu (Myrciaria dubia McVaugh, Myrtaceae) seed coat: a multivariate structure-activity study}, keyword = {inhibition of lipid oxidation DPPH, phenolic acids, flavonoids, food waste, HPLC-DAD} }
@article{article, author = {Fidelis, Marina and Santos, J\^{a}nio Sousa and Escher, Graziela Bragueto and Vieira do Carmo, Mariana and Azevedo, Luciana and Cristina da Silva, Marcia and Putnik, Predrag and Granato, Daniel}, year = {2018}, pages = {479-490}, DOI = {10.1016/j.fct.2018.07.043}, keywords = {inhibition of lipid oxidation DPPH, phenolic acids, flavonoids, food waste, HPLC-DAD}, journal = {Food and chemical toxicology}, doi = {10.1016/j.fct.2018.07.043}, volume = {120}, issn = {0278-6915}, title = {In vitro antioxidant and antihypertensive compounds from camu-camu (Myrciaria dubia McVaugh, Myrtaceae) seed coat: a multivariate structure-activity study}, keyword = {inhibition of lipid oxidation DPPH, phenolic acids, flavonoids, food waste, HPLC-DAD} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE

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