Pregled bibliografske jedinice broj: 1031542
Present criteria for prophylactic ICD implantation: Insights from the EU-CERT-ICD (Comparative Effectiveness Research to Assess the Use of Primary ProphylacTic Implantable Cardioverter Defibrillators in EUrope) project
Present criteria for prophylactic ICD implantation: Insights from the EU-CERT-ICD (Comparative Effectiveness Research to Assess the Use of Primary ProphylacTic Implantable Cardioverter Defibrillators in EUrope) project // Journal of electrocardiology, 19 (2019), 30415-10417 doi:10.1016/j.jelectrocard.2019.09.001 (međunarodna recenzija, pregledni rad, znanstveni)
CROSBI ID: 1031542 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Present criteria for prophylactic ICD implantation:
Insights from the EU-CERT-ICD (Comparative
Effectiveness Research to Assess the Use of Primary
ProphylacTic Implantable Cardioverter Defibrillators
in EUrope) project
Autori
Zabel, Markus ; Schlögl, Simon ; Lubinski, Andrzej ; Svendsen, Jesper Hastrup ; Bauer, Axel ; Arbelo, Elena ; Brusich, Sandro ; Conen, David ; Cygankiewicz, Iwona ; Dommasch, Michael ; Flevari, Panagiota ; Galuszka, Jan ; Hansen, Jim ; Hasenfuß, Gerd ; Hatala, Robert ; Huikuri, Heikki V. ; Kenttä, Tuomas ; Kucejko, Tomasz ; Haarmann, Helge ; Harden, Markus ; Iovev, Svetoslav ; Kääb, Stefan ; Kaliska, Gabriela ; Katsimardos, Andreas ; Kasprzak, Jaroslaw D. ; Qavoq, Dariusz ; Lüthje, Lars ; Malik, Marek ; Novotný, Tomáš ; Pavlović, Nikola ; Perge, Peter ; Röver, Christian ; Schmidt, Georg ; Shalganov, Tchavdar ; Sritharan, Rajeeva ; Svetlosak, Martin ; Sallo, Zoltan ; Szavits-Nossan, Janko ; Traykov, Vassil ; Vandenberk, Bert ; Velchev, Vasil ; Vos, Marc A. ; Willich, Stefan N. ; Friede, Tim ; Willems, Rik ; Merkely, Béla ; Sticherling, Christian
Izvornik
Journal of electrocardiology (0022-0736) 19
(2019);
30415-10417
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni
Ključne riječi
Implantable cardioverter defibrillator ; Mortality ; Risk factors ; Sudden cardiac death
Sažetak
BACKGROUND: The clinical effectiveness of primary prevention implantable cardioverter defibrillator (ICD) therapy is under debate. It is urgently needed to better identify patients who benefit from prophylactic ICD therapy. The EUropean Comparative Effectiveness Research to Assess the Use of Primary ProphylacTic Implantable Cardioverter Defibrillators (EU- CERT-ICD) completed in 2019 will assess this issue. SUMMARY: The EU-CERT-ICD is a prospective investigator-initiated non- randomized, controlled, multicenter observational cohort study done in 44 centers across 15 European countries. A total of 2327 patients with heart failure due to ischemic heart disease or dilated cardiomyopathy indicated for primary prophylactic ICD implantation were recruited between 2014 and 2018 (>1500 patients at first ICD implantation, >750 patients non-randomized non-ICD control group). The primary endpoint was all-cause mortality, and first appropriate shock was co- primary endpoint. At baseline, all patients underwent 12‑lead ECG and Holter-ECG analysis using multiple advanced methods for risk stratification as well as documentation of clinical characteristics and laboratory values. The EU-CERT-ICD data will provide much needed information on the survival benefit of preventive ICD therapy and expand on previous prospective risk stratification studies which showed very good applicability of clinical parameters and advanced risk stratifiers in order to define patient subgroups with above or below average ICD benefit. CONCLUSION: The EU- CERT-ICD study will provide new and current data about effectiveness of primary prophylactic ICD implantation. The study also aims for improved risk stratification and patient selection using clinical risk markers in general, and advanced ECG risk markers in particular.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
POVEZANOST RADA
Ustanove:
Medicinski fakultet, Rijeka,
KBC "Sestre Milosrdnice",
Klinički bolnički centar Rijeka
Profili:
Sandro Brusich
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE