Naslov
Hypovolemic shock and severe metabolic disturbances due to capecitabine therapy

Autori
Vucelić, Vesna ; Vučičević, Željko

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
Signa Vitae / - Zagreb : Signa Vitae, 2016, 84-84

Skup
22. Croatian International Symposium on Intensive Care Medicine

Mjesto i datum
Brijuni, Hrvatska, 14.06.2016. - 21.06.2016

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Podatak o recenziji nije dostupan

Ključne riječi
Hypovolemic shock, capecitabine, metabolic disturbances

Sažetak
We report on a rare case of severe hypovolemic shock, metabolic disturbances, coagulopathy, and prerenal insufficiency in a 72-year-old female patient treated with capecitabine. The patient underwent a total colectomy due to malignant descending colon obstruction and consecutive ishemic colitis. The oncologic therapy consisted of capecitabine in usual dosage regimen, but in spite of frequent and abundant diarrhoea on the seventh day, capecitabine therapy was continued for one more week. In the beginning of the treatment in the Intensive Care Unit, the daily stool volume loss was up to 7 liters, and the patient was not responsive to high doses of loperamide. Apart from intense supportive therapy, after 48 hours maximum recommended doses of octreotide infusions werw introduced. The daily stool volume was gradually reducet to normal, and the patient completely recovered with no signs of relapse.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA