%PDF-1.4
%
385 0 obj
<>
endobj
384 0 obj
<>stream
2019-10-11T09:45:47Z
2019-10-28T01:47:39-07:00
XPP
2019-10-28T01:47:39-07:00
application/pdf
Adobe LiveCycle PDF Generator
uuid:afd1eeb5-25a6-283a-5023-856b619f03b4
uuid:ee7115a7-1dd1-11b2-0a00-d200f81580ff
endstream
endobj
328 0 obj
<>
endobj
308 0 obj
<>
endobj
382 0 obj
<>
endobj
306 0 obj
<>
endobj
4 0 obj
<>
endobj
175 0 obj
<>
endobj
172 0 obj
<>/Font<>/ProcSet[/PDF/Text]/XObject<>>>/Rotate 0/TrimBox[9 9 603 792]/Type/Page>>
endobj
183 0 obj
<>/Font<>/ProcSet[/PDF/Text]/XObject<>>>/Rotate 0/TrimBox[9 9 603 792]/Type/Page>>
endobj
202 0 obj
<>/Font<>/ProcSet[/PDF/Text]/XObject<>>>/Rotate 0/TrimBox[9 9 603 792]/Type/Page>>
endobj
274 0 obj
<>/Font<>/ProcSet[/PDF/Text]/XObject<>>>/Rotate 0/TrimBox[9 9 603 792]/Type/Page>>
endobj
449 0 obj
<>/ProcSet[/PDF/Text]>>/Type/Page>>
endobj
467 0 obj
[472 0 R 473 0 R 474 0 R 475 0 R 476 0 R 477 0 R]
endobj
468 0 obj
<>stream
BT
/T1_0 1 Tf
12 0 0 12 273.672 653.99991 Tm
(Dora Visnjic)Tj
-14.6655 1 Td
(Vilma Dembitz, Barbara Tomic, Ivan Kodvanj, Julian A. Simon, Antonio Bed\
alov and)Tj
/T1_1 1 Tf
6.49752 1.00001 Td
(activating the ATR/Chk1 via pyrimidine depletion)Tj
-4.86051 1 Td
(The ribonucleoside AICAr induces differentiation of myeloid leukemia by)Tj
ET
BT
/T1_2 1 Tf
10 0 0 10 98 625.99997 Tm
(doi: 10.1074/jbc.RA119.009396 originally published online August 20, 201\
9)Tj
6.50199 1 Td
(2019, 294:15257-15270.)Tj
-6.50199 0 Td
(J. Biol. Chem.\240)Tj
ET
98 602 m
519 602 l
0 0 m
S
BT
ET
BT
/T1_0 1 Tf
10 0 0 10 98 557.99997 Tm
(\240 )Tj
/T1_3 1 Tf
36.01898 1 Td
( )Tj
0 0 1 rg
-12.11901 0 Td
(10.1074/jbc.RA119.009396)Tj
0 g
-23.89997 0 Td
(Access the most updated version of this article at doi: )Tj
ET
BT
/T1_0 1 Tf
10 0 0 10 129.11993 543 Tm
(\240)Tj
/T1_3 1 Tf
-3.11199 0 Td
(Alerts: )Tj
ET
BT
/T1_0 1 Tf
10 0 0 10 118 512.99994 Tm
(\240 )Tj
/T1_3 1 Tf
19.52397 1 Td
( )Tj
0 0 1 rg
-18.61797 0 Td
(When a correction for this article is posted)Tj
0 g
-0.906 0 Td
(\225\240 )Tj
11.68699 1.00001 Td
( )Tj
0 0 1 rg
-10.78099 0 Td
(When this article is cited)Tj
0 g
-0.906 0 Td
(\225\240 )Tj
ET
BT
/T1_3 1 Tf
10 0 0 10 142.44986 498 Tm
( to choose from all of JBC's e-mail alerts)Tj
0 0 1 rg
-4.44499 0 Td
(Click here)Tj
ET
BT
0 g
/T1_0 1 Tf
10 0 0 10 98 452.99994 Tm
(\240 )Tj
/T1_3 1 Tf
25.78895 1 Td
( )Tj
0 0 1 rg
-25.78895 0 Td
(http://www.jbc.org/content/294/42/15257.full.html#ref-list-1)Tj
0 g
0 1.00001 TD
(This article cites 42 references, 14 of which can be accessed free at)Tj
ET
BT
/T1_0 1 Tf
0 -8 8 0 587 387.05609 Tm
( by guest on October 28, 2019)Tj
0 0 1 rg
-7.88899 0 Td
(http://www.jbc.org/)Tj
0 g
-7.55399 0 Td
(Downloaded from )Tj
ET
endstream
endobj
454 0 obj
<>
endobj
469 0 obj
<>
endobj
470 0 obj
<>
endobj
471 0 obj
<>
endobj
472 0 obj
<>
endobj
473 0 obj
<>
endobj
474 0 obj
<>
endobj
475 0 obj
<>
endobj
476 0 obj
<>
endobj
477 0 obj
<>
endobj
483 0 obj
<>
endobj
482 0 obj
<>
endobj
481 0 obj
<>
endobj
480 0 obj
<>
endobj
479 0 obj
<>
endobj
478 0 obj
<>
endobj
464 0 obj
<>stream
HWYs8~ׯࣼe ^;Oqۙ5
Q6nV2T}l>p>E`5:!
l+$Q!E@ sEףq0*mޟIZ"o%'ȉnOg;s[=K?jsfw>=p?#
AOpڲ
#l\WН79
<mu_Cͺꖽ8oxx)<\ʭp`|)r]8Ӽk.YvΜhhDHG%D^#1mY80y:6$5]nۊam$gֱvP%]Q++XzPm+Igp(t2;GB{|GmnjEl,0EɩۈQ'F)RQsK,n!LP^&Ean}q
IuvI-!qQ&`f?_,zd+9mqnzxq[gw@-}HRL\WQF$"@z2+xfl>
fl1ֺ#l鶦iK :f_5C2)0 9ȉ5PJ:9KT,{j~̀i=>