Naslov
Effect of clonidine on the cutaneous silent period during spinal anesthesia

Autori
Graf Zupčić, Sandra ; Zupčić, Miroslav ; Đuzel, Viktor ; Šimurina, Tatjana ; Milošević, Milan ; Bašić, Silvio ; Vuletić, Vladimira ; Kapural, Leonardo

Izvornik
World Journal of Clinical Cases (2307-8960) 6 (2018), 16; 1136-1145

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Clonidine, Local anesthetics, Nerve fibers, Spinal anesthesia, Reflex

Sažetak
Cutaneous silent period (CSP) is an oligosynaptic spinal inhibitory reflex. The results of our study show that intrathecal administration of levobupivacaine with added clonidine, in comparison to levobupivacaine alone, yields a significantly shorter CSP and a significantly longer CSP latency during block regression following subarachnoid block (SAB) application. Accordingly, we can conclude that during SAB regression, a small dose of intrathecally administered clonidine ameliorates the inhibitory tonus and accelerates the conduction in the oligosynaptic spinal circuit.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti

POVEZANOST RADA