Naslov
Microscoping the amoeboid cell motility

Autori
Weber, Igor

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Proceedings from the 14th Multinational Congress on Microscopy, September 15–20, 2019, Belgrade, Serbia / Grbović Novaković, Jasmina ; Nestorović, Nataša ; Rajnović, Dragan - Beograd : University of Belgrade, Institute for Biological Research “Siniša Stanković”, National Institute of Republic of Serbia ; Serbian Society for Microscopy, Serbia, 2019, 30-30

ISBN
978-86-80335-11-7

Skup
14th Multinational Congress on Microscopy (MCM 2019)

Mjesto i datum
Beograd, Srbija, 15.09.2019. - 20.09.2019

Vrsta sudjelovanja
Plenarno

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
cell motility ; small GTPases ; amoeboid cell migration ; Dictyostelium ; light microscopy

Sažetak
Transition from mesenchymal to amoeboid cell migration is a hallmark of tumor metastasis. Genuine amoeboid motility is most appropriately studied in amoeba such as Dictyostelium. The core motility mechanisms conserved from amoebozoa to mammals are based on fast remodeling of the actin cytoskeleton regulated by small GTPases. I will present a retrospective of a quarter century of cell motility research in Dictyostelium and give an overview of the contemporary evolution of digital microscopy techniques with the focus on live cell imaging [1-15].

Izvorni jezik
Engleski

Znanstvena područja
Fizika, Biologija

POVEZANOST RADA