Pregled bibliografske jedinice broj: 1020307
RecBCD- RecFOR-independent pathway of homologous recombination in Escherichia coli
RecBCD- RecFOR-independent pathway of homologous recombination in Escherichia coli // FEMS Summer School for Postdocs
Split, Hrvatska, 2019. (pozvano predavanje, međunarodna recenzija, neobjavljeni rad, znanstveni)
CROSBI ID: 1020307 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
RecBCD- RecFOR-independent pathway of homologous
recombination in Escherichia coli
Autori
Zahradka, Davor
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, neobjavljeni rad, znanstveni
Skup
FEMS Summer School for Postdocs
Mjesto i datum
Split, Hrvatska, 28.08.2019. - 07.09.2019
Vrsta sudjelovanja
Pozvano predavanje
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
Recombination pathways ; RecBCD ; RecFOR ; sbcB15 mutation ; transduction ; DNA repair
Sažetak
A novel RecBCD- RecFOR-independent (RecBFI) recombination pathway is identified in E. coli. It operates in a specific genetic background, i.e. in sbcB15 sbcCD mutants. The RecBFI pathway strongly depends on recA, recJ and recQ gene functions, and moderately depends on recG and lexA functions. The key role in this pathway is played by the mutant SbcB15 protein (a defective ExoI that retained DNA-binding activity). SbcB15 facilitates loading of the RecA protein in the absence of functional RecBCD and RecFOR proteins.
Izvorni jezik
Engleski
Znanstvena područja
Biologija
POVEZANOST RADA
Projekti:
HRZZ-IP-2013-11-2978 - Rekombinacija, popravak DNA i očuvanje integriteta genoma: novi putevi (RECNEWPATH) (Zahradka, Davor, HRZZ - 2013-11) ( CroRIS)
Ustanove:
Institut "Ruđer Bošković", Zagreb
Profili:
Davor Zahradka
(autor)
