Naslov
Angiogenesis in CIN

Autori
Babić, Damir ; Jukić, Stanko ; Ilić Forko, Jadranka ; Čorušić, Ante ; Kos, Marina ; Ljubojević, Nikola ;

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Proceedings of the XI International Congress of Cervical Pathology and Colposcopy / Bordoy JC, Nicolau RL ; - Bolonja : Monduzzi Editore, 2002, 136-136

Skup
XI INTERNATIONAL CONGRESS OF CERVICAL PATHOLOGY AND COLPOSCOPXY

Mjesto i datum
Barcelona, Španjolska, 08.06.2002. - 14.06.2002

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
CIN; angiogenesis

Sažetak
Fifteen biopsy specimens of the uterine cervix were immunostained for CD 31 and F-VIII and analysed. The number and diameter of blood vessels was determined under the normal and metaplastic squamous epithelium, cylindrical endocervical epithelium and squamous epithelium showing changes from CIN I to CIN III. The depth of blood vessels position with regard to the tissue underlying the basement membrane in each specimen was also noted. The striking difference on the 1 mm of tissue length was noted at the basement membrane. The results demonstrate that a region of neovascularization develops along the basement membrane subtending dysplastic epithelium when compared to adjacent normal epithelium. Comparison of microvessel counts underlying normal epithelium, low grade lesions (condyloma and CIN I) with microvessel counts of CIN III lesions shows a statistically significant increase in the more advanced lesions

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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