Naslov
Prolonged Treatment of Eosinophilic Erythema Annulare with Chloroquine

Autori
Ljubojević Hadžavdić, Suzana ; Bartolić, Lucija ; Bradamante, Mirna

Izvornik
Acta dermatovenerologica Croatica (1330-027X) 26 (2018), 3; 262-263

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pismo, stručni

Ključne riječi
Eosinophilic annular erythema ; Wells syndrome ; antimalarials

Sažetak
Eosinophilic annular erythema (EAE) is a rare figurate dermatitis of unknown etiology with prominent tissue eosinophilia. A 59-year-old male patient presented with a one-month history of itchy, polycyclic, annular, and partially serpiginous lesions involving the back, the gluteal region, and the extremities. Clinically, EAE is characterized by asymptomatic or mildly pruritic urticarial papules and plaques in annular configuration, mainly on the trunk and proximal extremities. Histologically, as in our patient, EAE is characterized by the appearance of a superficial and deep perivascular inflammatory infiltrate composed of lymphocytes and abundant eosinophils and absence of epidermal change. There is no standard treatment for EAE. Systemic steroids and antimalarials are the usual first- line options. Other treatment options include dapsone, indomethacin, cyclosporine, and UVB therapy. Response to antimalarials is usually observed within the first 2-4 weeks. However, as in our case, it may take several weeks for patients to respond to antimalarial treatment, and complete regression may even take longer. We believe that EAE should be treated with antimalarials over a longer time period in order to avoid frequent relapses.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA