Naslov
Contact hypersensitivity in patients with psoriasis

Autori
Žužul, Kristina ; Kostović, Krešimir ; Čeović, Romana ; Ljubojević Hadžavdić, Suzana

Izvornik
Contact dermatitis (0105-1873) 78 (2018), 4; 287-289

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
contact allergy ; palmoplantar psoriasis ; patch test ; psoriasis

Sažetak
Psoriasis and contact dermatitis are common inflammatory skin diseases characterized by epithelial alterations and deviation in T cell immunity. Their prevalence in the general population is 1–3% and 15–20%, respectively. In psoriasis patients, keratinocytes show a higher proliferation rate and are less susceptible to apoptosis, while in allergic contact dermatitis (ACD) patients apoptosis is induced by T cells. Because of these antagonistic hallmarks, the extent to which patients with psoriasis develop ACD is unclear. Palmoplantar involvement in psoriasis patients is common, the frequency estimated to be 2–21.1%.The aims of this study were to determine the frequency of contact sensitization in patients with psoriasis who had palmar and/or plantar involvement, and to determine whether the palmoplantar involvement in patients with psoriasis is a manifestation of psoriasis or the expression of current or previous ACD.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA