Naslov
Poikilodermatous Mycosis Fungoides - Rare Entity, Different Treatment Modalities

Autori
Jerković Gulin, Sandra ; Čeović, Romana ; Ilić, Ivana ; Bradamante, Mirna ; Bukvić Mokos, Zrinka ; Kostović, Krešimir

Izvornik
Acta dermatovenerologica Croatica (1330-027X) 26 (2018), 1; 48-52

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, stručni

Ključne riječi
cutaneous T-cell lymphoma ; poikilodermatous mycosis fungoides ; poikiloderma vasculare atrophicans ; poikiloderma

Sažetak
Poikilodermatous mycosis fungoides (PMF) is a rare clinical variant of early-stage MF with peculiar histological features. Poikiloderma occurs in many different clinical conditions, which makes a diagnostic procedure more complicated. PMF belongs to a group of MF variants with low risk of disease progression. We report a case of a 64-year-old woman, who presented with mottled skin aspect of erythema, poikilodermatous patches (hypopigmentation, hyperpigmentation, atrophy, and telangiectasia) on more than 80% of the body. Based on clinical, histopathological, and immunohistochemical findings, we established the diagnosis of PMF. Staging procedure determined stage IIA. As skin-directed therapy was the treatment of choice, the patient was successfully treated with psoralen-UVA (PUVA), nbUVB plus retinoid (Re-nbUVB), and PUVA plus retinoid (Re- PUVA), however, with rapid recurrence.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA