Naslov
The identification of war victims by reverse paternity is associated with significant risks of false inclusion

Autori
Gornik, Ivan ; Marcikić, Mladen ; Kubat, Milovan ; Primorac, Dragan ; Lauc, Gordan

Izvornik
International Journal of Legal Medicine (0937-9827) 116 (2002), 5; 255-257

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
STR sequences; Amplified Fragment Length Polymorphism; DNA typing; Human identity; Paternity

Sažetak
Since February 2001 the process of DNA identification of war victims in Croatia relies on the database of over 3, 000 nine-loci (D3S1358, vWA, FGA, TH01, TPOX, CSF1PO, D5S818, D13S317 and D7S820) STR genotypes of relatives of missing persons. Instead of a targeted approach to DNA typing, the genotype of each analyzed skeletal remains is compared to all genotypes in the database to identify potential parents and children. Although this approach has significantly increased the pace of identification by DNA typing, non-targeted matching in a database containing several thousand genotypes considerably decreases the significance of inclusion, especially when identification is based on reverse paternity analysis. To support this statistical prediction we are presenting three cases of 10 STR loci match and one case of 11 STR loci match between a child, child's mother and skeletal remains that did not originate from a father of that child.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Temeljne medicinske znanosti, Javno zdravstvo i zdravstvena zaštita

POVEZANOST RADA