Naslov
Complication and prognosis of juvenile idiopathic arthritis associated uveitis in the era of modern immunomodulatory

Autori
Barišić Kutija, Marija ; Perić, Sanja ; Knežević, Josip ; Juratovac, Zlatko ; Vukojević, Nenad

Izvornik
Psychiatria Danubina (0353-5053) 31 (2019); 44-49

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
juvenile idiopathic arthritis ; uveitis ; functionally eye damage ; structurally eye damage ; quality of life

Sažetak
IA is the most common rheumatic disease of childhood and JIA-U is its most frequent and most devastating extraarticular manifestation. This form of uveitis is usually asymptomatic, chronic anterior uveitis, often accompained with complications. JIA-U is the main cause of vision loss and even blidness in childhood. Thus, screening for JIA-U in all JIA patients and early treatment is of prime importance. Over the last 15-20 years, ever since IMT has been used, studies generally show trends toward decrease of JIA-U onset, complications frequency, improvement of prognosis and remission achievement. Despite evident improvements, over 20% JIA-U patients still develop complications in long-term follow- up. Moreover, about 50% JIA-U patients continue to have active uveitis in adulthood. Therefore, JIA-U is still associated with high risk of late sequelae and visual acuity loss, functionally and structurally eye damage and quality of life impairment.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA