Pregled bibliografske jedinice broj: 100901
Histochemica investigations of nadph- and nadh-tetrazolium reductase activity in the liver of selenium and copper treated carp (Cyprinus carpio L.)
Histochemica investigations of nadph- and nadh-tetrazolium reductase activity in the liver of selenium and copper treated carp (Cyprinus carpio L.) // Veterinarski arhiv, 74 (2004), 5; 331-340 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 100901 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Histochemica investigations of nadph- and nadh-tetrazolium reductase activity in the liver of selenium and copper treated carp (Cyprinus carpio L.)
Autori
Gorup, Margita ; Kralj-Klobučar, Nada
Izvornik
Veterinarski arhiv (0372-5480) 74
(2004), 5;
331-340
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
NADPH- and NADH-tetrazolium reductase; histochemistry; selenium; copper; liver; carp
Sažetak
Histochemical methods were employed to examine the effects of selenium and copper intoxication on NADPH- or NADH-tetrazolium reductase activity in liver tissue. Both enzymes were located in the intracellular granules though NADH-tetrazolium reductase also showed diffuse distribution in the cytoplasm. The granules in which the activity of both enzymes was demonstrated represent mitochondria, while the activity of NADH-TR in the cytoplasm refers to the endoplasmic reticulum. The results showed that selenium and copper in concentrations of 0.1 mg/L did not induce changes in NADPH-TR activity. The activity of NADH-TR in the mitochondria oscillated throughout the treatment period with both elements, while copper also induced a significant increase of enzyme activity in the cytoplasm. Prolonged intoxication with both selenium and copper lead to damages in liver tissue and the reduction of activity for both enzymes.
Izvorni jezik
Engleski
Znanstvena područja
Biologija
Citiraj ovu publikaciju:
Časopis indeksira:
- Scopus
