Pregled bibliografske jedinice broj: 1007394
Chiral phosphoric acid-catalyzed enantioselective construction of structurally diverse benzothiazolopyrimidines
Chiral phosphoric acid-catalyzed enantioselective construction of structurally diverse benzothiazolopyrimidines // Chemical science, 10 (2019), 13; 3765-3769 doi:10.1039/c8sc05581e (međunarodna recenzija, članak, znanstveni)
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Naslov
Chiral phosphoric acid-catalyzed enantioselective
construction of structurally diverse
benzothiazolopyrimidines
Autori
Jarrige, Lucie ; Glavač, Danijel ; Levitre, Guillaume ; Retailleau, Pascal ; Bernadat, Guillaume ; Neuville, Luc ; Masson, Géraldine
Izvornik
Chemical science (2041-6520) 10
(2019), 13;
3765-3769
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
asymmetric organocatalysis ; chiral Brønsted acid ; benzothiazolopyrimidines ; Lewis base isothiourea derivatives ; homobenzotetramisole (HBTM)
Sažetak
A highly efficient catalytic enantioselective [4+2] cycloaddition was developed between 2- benzothiazolimines and enecarbamates. A wide range of benzothiazolopyrimidines bearing three contiguous stereogenic centers was obtained in high to excellent yields and with excellent diastereo- and enantioselectivities (d.r. > 98 : 2 and up to >99% ee). Furthermore, this chiral phosphoric acid- catalyzed strategy was scalable and enabled access to a new class of optically pure Lewis base isothiourea derivatives.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- Nature Index
