Naslov
Intraarticular synovial sarcoma of the knee rising from a lateral meniscus – a case report

Autori
Bergovec, Marko ; Smerdelj, Miroslav ; Bacan, Filip ; Seiwerth, Sven ; Herceg, Davorin ; Prutki, Maja

Izvornik
Orthopaedics & Traumatology-Surgery & Research (1877-0568) 104 (2018), 2; 227-230

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Synovial sarcoma ; Diagnostic molecular pathology ; Arthroscopy ; Knee prosthesis

Sažetak
Synovial sarcoma (SS) is a rare mesenchymal tumor, accounting less than 10% of soft tissue sarcomas. We report a case of intraarticular SS mimicking nodular synovitis and lateral meniscus rupture. Due to clinical and radiological presentation, arthroscopic synovectomy was performed, and histology confirmed nodular synovitis. After four years the lesion recurred and new arthroscopic biopsy was performed, revealing a monophasic SS with SYT/SSX1 translocation. Repeated histology of the first specimen confirmed appearance of a nodular synovitis microscopically, with no morphological criteria for a sarcoma, but molecular analysis showed positive SYT/SSX1 translocation. Wide extraarticular knee resection and reconstruction with a tumor megaendoprosthesis-allograft composite was performed with a negative tumor margins. This case report showed that in a case of benign histological appearance, underlying sarcoma is possible and could be identified in early stages only with an advanced pathology methods.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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