Naslov
Contact allergic dermatitis to fragrance mix

Autori
Milavec-Puretić, Višnja ; Lipozenčić, Jasna

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
Acta Dermatovenerologica Croatica / Lipozenčić, Jasna - Zagreb : Glafoplast, Zagreb, 2002, 100-101

Skup
Second Congress of Croatian Dermatovenerologists with International participation "New Highlights in Dermatovenerology"

Mjesto i datum
Opatija, Hrvatska, 16.05.2002. - 19.05.2002

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
contact allergic dermatitis; fragrance mix; photodermatitis; contact urticaria

Sažetak
Contact allergic dermatitis (CAD) is a classic Coombs and Cell type IV delayed hypersensitivity reaction. It is a most common reaction seen by practicing dermatologists to fragrance materials. The mix detects possibly 70-80% of fragnance sensitivity. It is one of the most frequently positive allergens in the European standard series, and in many countries it rates second after nickel sulfate. Photodermatitis is seen occasionally, as is contact urticaria, irritation, and depigmentation. Fragrances have widespread use and are found not only in cosmetics but also in detergents, fabric softeners, toothpastes, and sanitary pads. The fragnance mixture is a combination of the most common fragrance allergens detected over the last several years. It consists of the following eight chemicals, at a 2% concentration in petrolatum:cinnamic aldehyde 4%, cinnamic alcohol 2%, isoeugenol 2%, hydroxycitronellal 1.4%, oak moss 1.2%, eugenol 1%, geraniol 0.2%, alpha amyl cinnamic alcohol 0.2%. Balsam of Peru (in-standard battery) is a marker of fragrance sensitivity and is positive in about 50% of cases of perfume allergy and in our study we have found 47%. Patch testing with a fragrance “ mixture” may occasionally give nonspecific irritant reactions. Any "positive" reaction to this mixture should be followed by positive patch testing with the individual components. Some investigators have reported an increse in the frequency of positive reactions to fragrance mix during the last two decades. The aim of this study was to determine the incidence of allergy to fragrance mixture during a one-year period at the Allergy Clinic Dept. of Dermatology and Venerology, Zagreb University Hospital Center, Zagreb, Croatia.During the one year period out of 1122 patients submitted to patch testing for delayed type sensitivity, 144(12, 8%) showed positive reaction to fragrance mixture(43 males, 111 females), age rang: 40, 5 years. In all patients, patch(epicutaneous) test was applied in accordance with the International Contact Dermatitis Research Group(ICDRG) recommendations. In patients only allergy to fragrance mixture was observed and also to each of eight components of the mixture. Contact allergy was mostly on face, neck and hands. Our data suggests that there is a great percent of patients positive to fragrance mixture in patch test.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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