Pregled bibliografske jedinice broj: 1003293
Local immunity in the skin : The skin immune system (SIS)
Local immunity in the skin : The skin immune system (SIS) // Acta dermatovenerologica Croatica, 6 (1998), 3; 135-139 (međunarodna recenzija, članak, stručni)
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Naslov
Local immunity in the skin : The skin immune system (SIS)
Autori
Silobrčić, Vlatko ; Harjaček, Miroslav
Izvornik
Acta dermatovenerologica Croatica (1330-027X) 6
(1998), 3;
135-139
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, stručni
Ključne riječi
cytokine: icosanoid ; neuropeptide ; plasmin ; secretory immunoglobulin ; immune system
Sažetak
The skin, as the body's interface with the environment, is a unique immunological microenvironment. The skin immune system (SIS) is a complex of local immunocompetent cells and their products. Its cellular component consists of: keratinocytes, tissue macrophages, monocytes, granulocytes, mastocytes, Langerhans cells, tissue dendritic cells, T lymphocytes and endothelial cells. The humoral component includes: fibrinolysins, antimicrobial peptides, components of the complement, eicosanoids, neuropeptides, secretory immunoglobulins and a network of cytokines. SIS is continually exposed to agents from the environment (sun rays, toxins, antigens, microbes). It reacts by inflammation and immunoreaction. The cytokines, produced by the epidermal cells, regulate the whole process.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
POVEZANOST RADA
Ustanove:
Hrvatska akademija znanosti i umjetnosti,
Medicinski fakultet, Zagreb,
KBC "Sestre Milosrdnice",
Dječja bolnica Srebrnjak
Citiraj ovu publikaciju:
Časopis indeksira:
- Scopus