Naslov
Lymphoid and myeloid cell subsets in pigs immunized with F4ac^+ nonenterotoxigenic Escherichia coli (non-ETEC) strain

Autori
Šver, Lidija ; Malešević, Aleksandra ; Lacković, Gordana ; Haverson, Karin ; Popović, Maja ; Valpotić, Ivica

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
2001 Annual Meeting of the Croatian Immunological Society / - Zagreb : Hrvatsko imunološko društvo, 2001, 21-21

Skup
2001 Annual Meeting of the Croatian Immunological Society

Mjesto i datum
Zagreb, Hrvatska, 07.12.2001

Vrsta sudjelovanja
Poster

Vrsta recenzije
Domaća recenzija

Ključne riječi
Pig; oral vaccine; Escherichia coli; gut-associated lymphoid tissue

Sažetak
We have evaluated immunogenicity of F4ac^+ non-ETEC strain Abbotstown A in the specific immunization of weaned pigs based on the qualitative and quantitative parameters of the local (intestinal) immunity. Orogastric immunization of pigs with 10^10 CFU/mL of F4ac^+ non-ETEC strain Abbotstown A induced increase in relative proportions of lymphoid and myeloid cells from the mesenteric lymph node, especially of B-lymphocytes and macrophages. The relative proportions of SWC8+ lymphoid and SWC3^+ myeloid cells were increased in the ileal Peyer's patches of immunized pigs. The results indicate increased proportions of lymphoid and myeloid cells in gut-associated lymphoid tissues (GALT) of immunized pigs, and thus, solid immunogenicity of live oral vaccine against postweaning colibacillosis. We assume that our study will contribute to a better understanding of induction and regulation of the immune reactions in the GALT of weaned pigs primed with vaccinal antigens of E. coli strai applied as an immunogen.

Izvorni jezik
Engleski

Znanstvena područja
Veterinarska medicina

POVEZANOST RADA