Naslov
Influence of surface morphology and structure of alginate microparticles on the bioactive agents release behavior

Autori
Jurić, Slaven ; Šegota, Suzana ; Vinceković, Marko

Izvornik
Carbohydrate polymers (0144-8617) 218 (2019); 234-242

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
alginate microparticles ; biofertilizer ; release mechanism ; structure/property relationship ; Trichoderma viride

Sažetak
The structure-property relationship in alginate microparticles (microspheres and microcapsules prepared with or without Trichoderma viride spores (Tv) was investigated. Surface morphology, structure and release behavior from alginate microparticles strongly depend on calcium concentration and presence of Tv and chitosan layer. All microparticles exhibited a granular surface structure with substructures consisting of abundant smaller particles. In vitro active agents release study revealed that the increase in calcium cation concentration reduced the release rate of Tv (~84% for microspheres ; ~57% for microcapsules) and calcium cations (~20% for microspheres ; ~23% for microcapsules). The average decrease in k values due to chitosan layer addition is 41% for Tv and 93% for calcium ions, respectively. The underlying Tv release mechanism from microspheres is anomalous transport kinetics, whereas from microcapsules is controlled by Type II transport. The differences in microparticle surface properties did not affect the mechanism controlling calcium ions release detected as diffusion through microparticles.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

POVEZANOST RADA