Naslov
Combined multichannel intraluminal impedance-pH monitoring should be used to diagnose reflux-related otitis media with effusion in children

Autori
Pavić, Ivan ; Babić, Irena ; Matijašić, Nuša ; Hojsak, Iva

Izvornik
Acta paediatrica (Oslo) (0803-5253) 107 (2018), 9; 1642-1647

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
children ; gastroesophageal reflux ; impedance ; otitis: pH monitoring

Sažetak
This study investigated the diagnostic usefulness of combined multichannel intraluminal impedance‐pH monitoring (MII‐pH) in children with suspected reflux‐related otitis media with effusion (OME) as existing data were scarce. This was a prospective study that included children up to seven years of age who underwent MII‐pH due to OME lasting more than three months. The study was conducted in the Children's Hospital Zagreb, Croatia, from January 2014 to August 2016. The study comprised 63 children (63% male) with a mean age of 4.7 years. Gastroesophageal reflux (GER) disease was detected by impedance in 22 (35%) of the children and by pH‐metry in nine (14%). In children with OME, MII‐pH found a median number of 24 proximal GER episodes, of which a median of nine was acidic and a median of 11 was weakly acidic. There was a significant positive correlation between the number of GER episodes and the presence of eosinophils in nasal swabs. Both acidic and weakly acidic refluxes seemed to play a significant role in the pathogenesis of OME. Localised nasal eosinophilia may serve as a marker of extraoesophageal reflux in children with suspected reflux‐related OME.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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