Naslov
Progressive encephalomyelitis with rigidity: a case report.

Autori
Baraba, Ranka ; Jušić, Anica ; Sruk, Ana

Izvornik
Journal of spinal cord medicine (1079-0268) 33 (2010), 1; 73-76

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, stručni

Ključne riječi
Spasticity, Muscle spasms, tonic, Encephalomyelitis, progressive, Corticosteroid therapy, Methylprednisolone, Magnetic resonance imaging, Decerebrate posture

Sažetak
Background/Objective: The most prominent clinical features of progressive encephalomyelitis with rigidity (PER) are painful spasms and rigidity accompanied by clinical signs of brainstem and spinal cord involvement. In initial reports, PER had fatal outcome. Later, clinical improvement related to corticosteroid therapy has been described in some cases. The objective of this study was to signify a reputed clinical significance of corticosteroid therapy in PER. Methods: Case report. Results: A 50-year-old man developed progressive syndrome of tonic extensor spasms. Magnetic resonance imaging (MRI) showed areas of signal changes in cervical spinal cord and lower brainstem, whereas cerebrospinal fluid analysis indicated subacute encephalomyelitis. His condition dramatically improved on oral corticosteroid therapy. Clinical improvement was accompanied by normalization of MRI findings. Conclusion: For this patient with PER, corticosteroid therapy was a dramatically effective and life-saving treatment, although initiated rather late in the course of the disease.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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