Naslov
EPR study of ion substituted hydroxy apatites

Autori
Grego, Timor ; Čolović, Božana ; Erceg, Ina ; Dutour Sikirić, Maja ; Maltar-Strmečki, Nadica

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Molecular Biophysics: ABC of the puzzle of Life, Book of Abstracts ; March 18-20, 2019, Zagreb, Croatia / Ivošević Denardis, Nadica ; Campos-Olivas, Ramon ; Miele, E. Adriana ; England, Patrick ; Vuletić, Tomislav - Zagreb : Institut Ruđer Bošković ; Hrvatsko biofizičko društvo, 2019, 103-104

ISBN
978-953-7941-28-4

Skup
The 3rd COST-sponsored AMBRE-MOBIEU plenary meeting "Molecular Biophysics: ABC of the puzzle of Life" March 18-20, 2019, Zagreb, Croatia

Mjesto i datum
Zagreb, Hrvatska, 18.03.2019. - 20.03.2019

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
hydroxy apatites ; EPR ; ionic substitution

Sažetak
Since calcium phosphates (CP) constitute the main mineral component of the hard tissues of vertebrates, their synthetic analogues are the most commonly used materials in orthopedics and stomatology [1-3]. Namely, the mineral phase of the bones and teeth is a basic calcium phosphate, which is being equalized with synthetic calcium hydroxyapatite (HA, Ca10(PO4)6(OH)2) [2]. However, biological apatites differ from stoichiometric HA in several aspects, such as non-stoichiometry, small crystal sizes and poor crystallinity which are important factors associated with the relatively high solubility of biological apatites compared to stoichiometric HA [2]. Biological apatites are actually carbonated apatites containing also foreign ions, which can be incorporated in or adsorbed on the apatite crystal surface. Synthesis of differently ion substituted HA is attracting attention in developing novel biomaterials with increased bioactivity, as well as possibility to deliver ions for treatment of the diseased bone [2, 4]. Among key questions for optimizing the synthetic procedures and producing efficient biomaterials is how different ions modify crystal and surface structure of HA. The aim of this study was to determine the influence of Mg and Si on short range ion arrangement in synthetic HA by EPR (electron paramagnetic resonance) spectroscopy. HA modified with Mg and Si were synthetized by hydrothermal procedure. Their structure and morphology were determined by powder X-ray diffraction and scanning electron microscopy. For EPR investigation, the gamma radiation induced radical were used as probes to follow and control the changes in relation with substituted ions. The obtained results provide better insight in the influence of ionic substitution on HAP structure and therefore can be used in designing of HAP with specific properties.

Izvorni jezik
Engleski

Znanstvena područja
Fizika, Kemija, Interdisciplinarne prirodne znanosti

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