Pregled bibliografske jedinice broj: 990374
First total synthesis of ent-asperparaline C and assignment of the absolute configuration of asperparaline C
First total synthesis of ent-asperparaline C and assignment of the absolute configuration of asperparaline C // Chemical communications, 55 (2019), 27; 3931-3934 doi:10.1039/C9CC00945K (međunarodna recenzija, članak, znanstveni)
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Naslov
First total synthesis of ent-asperparaline C and assignment of the absolute configuration of asperparaline C
Autori
Dokli, Irena ; Pohl, Radek ; Klepetářová, Blanka ; Jahn, Ullrich
Izvornik
Chemical communications (1359-7345) 55
(2019), 27;
3931-3934
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Asperparaline C ; Total synthesis ; Absolute configuration ; Alkaloids ; Radical Cyclization
(Asperparaline C ; Total synthesis ; Absolute configuration ; Alkaloids ; Radical cyclization)
Sažetak
The first asymmetric total synthesis of a member of the asperparaline family was accomplished and the unknown absolute configuration of asperparaline C has been determined to be all-(S). The key steps of the synthesis are an oxidative radical cyclization, a selective reduction of one of the tertiary amides, a singlet oxygen Diels–Alder reaction and a reductive spirocyclization.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
- Nature Index
