Pregled bibliografske jedinice broj: 985825
Expression of Superoxide Dismutase Enzyme in Stress Condition
Expression of Superoxide Dismutase Enzyme in Stress Condition // Book of Abstracts. Special Issue of Bulletin of the Chemists and Technologists of Bosnia and Herzegovina. / Korać, Fehim (ur.).
Sarajevo: Glas hemičara i tehnologa Bosne i Hercegovine, 2016. str. 18-18 (predavanje, međunarodna recenzija, sažetak, znanstveni)
CROSBI ID: 985825 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Expression of Superoxide Dismutase Enzyme in Stress Condition
Autori
Politeo, Olivera ; Carev, Ivana ; Ferhatović Hamzić Lejla
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
Book of Abstracts. Special Issue of Bulletin of the Chemists and Technologists of Bosnia and Herzegovina.
/ Korać, Fehim - Sarajevo : Glas hemičara i tehnologa Bosne i Hercegovine, 2016, 18-18
Skup
2nd International Congress of Chemists and Chemical Engineers of Bosnia and Herzegovina.
Mjesto i datum
Sarajevo, Bosna i Hercegovina, 21.10.2016. - 23.10.2016
Vrsta sudjelovanja
Predavanje
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
SOD ; rat model ; stress conditions ; WST method
Sažetak
Reactive oxygen species (ROS) play a key role in the initiation and progression of many human diseases. Superoxide anion radical (O2•-), arising continuously in the cells, is one of the most important and biologically relevant ROS radicals in living organisms. Superoxide dismutase (SOD) is an enzyme important in the process of cellular responses to stress conditions. Using WST spectrophotometric method, it is investigated the effect of insulin dependent diabetes mellitus (IDDM) on the SOD expression of tissues in aging rats. For this purpose, rat model for IDDM was established by streptozotocin application. The rats were randomly divided into 4 groups of animals: DM-2W (streptozotocin treated and sacrificed after 2 weeks of diabetes), control-2W (control group sacrificed after 2 weeks of the experiment), DM- 1Y (streptozotocin treated and sacrificed after 1 year of diabetes) and control-1Y (control group sacrificed after 1 year of the experiment). Results showed overexpression of SOD enzyme in both of DM-2W and DM-1Y groups compared with control groups of rats. In comparison the expression of the enzyme in both of DM-2W and DM-1Y groups, the stronger overexpression of the enzyme in the first one group was registered. That could be explained by fading of defence system of organism.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
POVEZANOST RADA
Projekti:
HRZZ-IP-2014-09-6897 - Istraživanje bioaktivnih spojeva iz dalmatinskog bilja: njihov antioksidacijski karakter i utjecaj na enzimsku inhibiciju i zdravlje (BioActCom) (Miloš, Mladen, HRZZ - 2014-09) ( CroRIS)
Ustanove:
Kemijsko-tehnološki fakultet, Split
