Naslov
Myocardial Infarction and Circadian Rhythm

Autori
Škrlec, Ivana ; Marić, Svjetlana ; Včev, Aleksandar

Vrsta, podvrsta i kategorija rada
Poglavlja u knjigama, pregledni

Knjiga
Visions of Cardiomyocyte - Fundamental Concepts of Heart Life and Disease

Urednik/ci
Tsipis, Angelos

Izdavač
IntechOpen

Grad
London : Delhi

Godina
2020

Raspon stranica
21-35

ISBN
978-953-51-8094-4

Ključne riječi
cardiomyocytes ; circadian rhythm ; myocardial infarction

Sažetak
Human physiological activity and condition during illness are under the control of the circadian rhythm. Circadian rhythms handle a wide diversity of physiological and metabolic functions, and the interruption of these rhythms has been linked to obesity, sleep disorders, metabolic and psychological disorders, and cardiovascular events such as myocardial infarction (MI), stroke, and vascular death. Disruption of circadian rhythms increases the risk of developing myocardial infarction, indicating that circadian genes might play an essential role in determining disease susceptibility. It is well known that many cardiovascular processes show daily variations depending on the circadian rhythm (blood pressure, heart rate), and the gene expression of the cardiomyocyte circadian clock influences myocardial contractile function, metabolism, and other gene expressions. We present a review of the latest knowledge on the impact of circadian rhythm and circadian rhythm genes on myocardial infarction. Today, in a time of personalized medicine, it is essential to know each person’s circadian rhythm for its treatment and possible inclusion in the diagnostic procedures.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Temeljne medicinske znanosti, Kliničke medicinske znanosti

POVEZANOST RADA