Pregled bibliografske jedinice broj: 977890
Mixed Copolymer Adlayers Allowing Reversible Thermal Control of Single Cell Aspect Ratio
Mixed Copolymer Adlayers Allowing Reversible Thermal Control of Single Cell Aspect Ratio // ACS applied materials & interfaces, 10 (2018), 3; 2253-2258 doi:10.1021/acsami.7b18513 (međunarodna recenzija, članak, znanstveni)
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Naslov
Mixed Copolymer Adlayers Allowing Reversible Thermal
Control of Single Cell Aspect Ratio
Autori
Dalier, F. ; Dubacheva, G. V. ; Coniel, M. ; Zanchi, D. ; Galtayries, A. ; Piel, M. ; Marie, E. ; Tribet, C.
Izvornik
ACS applied materials & interfaces (1944-8244) 10
(2018), 3;
2253-2258
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
cell polarization ; cell adhesion ; poly(lysine) ; poly(N-isopropylacrylamide) ; peptide display
Sažetak
Dynamic guidance of living cells is achieved by fine- tuning and spatiotemporal modulation on artificial polymer layers enabling reversible peptide display. Adjustment of surface composition and interactions is obtained by coadsorption of mixed poly(lysine) derivatives, grafted with either repellent PEG, RGD adhesion peptides, or T-responsive poly(N- isopropylacrylamide) strands. Deposition of mixed adlayers provides a straightforward mean to optimize complex substrates, which is here implemented to achieve (1) thermal control of ligand accessibility and (2) adjustment of relative adhesiveness between adjacent micropatterns, while preserving cell attachment during thermal cycles. The reversible polarization of HeLa cells along orthogonal stripes mimics guidance along natural matrices.
Izvorni jezik
Engleski
Znanstvena područja
Fizika, Biologija
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
