Pregled bibliografske jedinice broj: 9735
Modulation of cytochrome P450 1A in sea bass liver by model substances and sea water extracts
Modulation of cytochrome P450 1A in sea bass liver by model substances and sea water extracts // Aquatic toxicology, 40 (1998), 2-3; 265-273 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 9735 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Modulation of cytochrome P450 1A in sea bass liver by model substances and sea water extracts
Autori
Jakšić, Željko ; Bihari, Nevenka ; Mueller, Werner E.G. ; Zahn, Rudolf K. ; Batel, Renato
Izvornik
Aquatic toxicology (0166-445X) 40
(1998), 2-3;
265-273
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
fish; cytochrome P450 1A; EROD; seawater extracts
Sažetak
Immunochemical and catalytic assays for cytochrome P450 1A induction in liver of sea bass Dicentrarchus labrax treated with different model substances and organic sea water extracts have been performed. Etoxyresorufin-O-deethylase (EROD) activities in fish liver were elevated by Arochlor 1254 (Aro), 3-methylcholanthrene (MC) and ß-naphtoflavone (ßNF), but not by phenobarbital (PB) treatment. Elevated levels of P450 1A protein followed by induction of EROD activity were detected only in ßNF treated fish. Treatment of fish with organic sea water extracts revealed that there is no simple correlation between EROD activities and its catalyst P450 1A level. Sea water extracts are mixtures of chemicals that have the ability to suppress the levels of P450 1A and/or to inhibit EROD activity.
Izvorni jezik
Engleski
Znanstvena područja
Biologija
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
