Naslov
Salivary Morning Cortisol and Sleep Quality in Healthy Subjects

Autori
Knezović Zlatarić, Dubravka ; Alajbeg, Iva ; Roglić, Dunja ; Alajbeg, Ivan ; Illeš, Davor ; Vuletić, Lea ; Andabak Rogulj, Ana ; Lapić, Ivana ; Badel, Tomislav

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Journal of Dental Research / Giannobile, William V - : International Association for Dental Research, 2017, 2955-2955

Skup
IADR/AADR/CADR General Session

Mjesto i datum
San Francisco (CA), Sjedinjene Američke Države, 20.03.2017. - 25.03.2017

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
salivary awakening cortisol ; healthy adults

Sažetak
Objectives: The aim of this study was to determine the normal inter- day variations of salivary awakening cortisol in healthy adult individuals and to explore its relationship with sleep quality as measured by Sleep cycle alarm clock. Methods: Sleep quality Fifteen adult subjects, 9 females and 6 males, (mean age 38.73±5.18 years), with no previously diagnosed sleep disorders, were included in the study. Subjects were asked to download the free version of the app Sleep cycle alarm clock (Northcube AB 8 Göteborg, Sweden) onto their iPhones through the App Store. All subjects were required to use the app for a minimum of 5 nights at home before participating in the study. After they had used the app for a minimum of 5 nights, subjects used the app for three consecutive nights. Sleep quality < 81% was considered as poor sleep quality . Morning Salivary Awakening Cortisol Assessment Five millilitres of whole unstimulated saliva was collected into a graduated tube (50 ml, self- standing centrifuge tubes, Ratiolab, Germany).Subjects were asked to collect saliva immediately after waking up during three consecutive days. Saliva aliquots, (1 ml), were stored at −80°C until analysed. Saliva samples were thawed and centrifuged prior to analysis (1000xg, 5 min). Salivary free cortisol levels were determined using a competitive ELISA kit (Demeditec Diagnostics GmbH, Germany). Results: Intra-individual variability for morning cortisol was 15- 42%. Objective poor sleepers (sleep quality < 81%) had significantly lower salivary awakening cortisol than good sleepers. Conclusions: Our study shows that the poor sleep quality, measured by Sleep cycle alarm clock for iPhones was associated with decreased salivary awakening cortisol.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Dentalna medicina

POVEZANOST RADA