Pregled bibliografske jedinice broj: 967741
Treatment and skin decontamination of sarin intoxicated mice
Treatment and skin decontamination of sarin intoxicated mice // Toxicological and environmental chemistry, 100 (2018), 3; 361-371 doi:10.1080/02772248.2018.1523413 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 967741 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Treatment and skin decontamination of sarin intoxicated mice
Autori
Vučemilović, Ante ; Hadžija, Mirko ; Žuntar, Irena
Izvornik
Toxicological and environmental chemistry (0277-2248) 100
(2018), 3;
361-371
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Treatment ; mice ; mineral cationic carrier (MCC) ; sarin ; skin decontamination
Sažetak
This study aimed at evaluating the efficacy of oral treatment and skin decontamination with the mineral cationic carrier in sarin-intoxicated mice. Mice were contaminated with increasing percutaneous sarin doses and decontaminated. Furthermore, the surviving mice were treated per os. The behavioral patterns of the surviving animals were monitored for 72 h, including the animals ’ posture, desire for food and water, and approach and touch response. The results showed the mineral cationic carrier to be capable of efficiently decontaminating animals percutaneous poisoned with triple lethal dose. The comparison of behavioral pattern of control animals against those treated per os showed statistically significant differences. Oral treatment with mineral cationic carrier may be a detoxification tool against nerve agents ’ poisoning, and this merits further research.
Izvorni jezik
Engleski
Znanstvena područja
Biologija, Temeljne medicinske znanosti, Farmacija
POVEZANOST RADA
Ustanove:
Farmaceutsko-biokemijski fakultet, Zagreb,
Institut "Ruđer Bošković", Zagreb,
Sveučilište u Zagrebu
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
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- AGRICOLA
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- CA Search (Chemical Abstracts)
- Compendex (EI Village)
- Geobase
- GeoRef
- BIOBASE
- CABI
- CSA
- De Gruyter Saur
- EBSCOhost
- OCLC
- ProQuest
