Naslov
The Solvent Influence on the Complexation of Amphiphilic Mannosides with β-cyclodextrin

Autori
Požar, Josip ; Leko, Katarina ; Car, Željka ; Pičuljan, Katarina ; Draženović, Josip ; Petrović Peroković, Vesna ; Ribić Rosana

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
3rd International Congress of Chemists and Chemical Engineers of Bosnia and Herzegovina : Book of Abstracts / Korać, Fehim - Sarajevo, 2018, 112-112

Skup
3rd International Congress of Chemists and Chemical Engineers of Bosnia and Herzegovina

Mjesto i datum
Sarajevo, Bosna i Hercegovina, 19.10.2018. - 21.10.2018

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
cyclodextrin ; inclusion complexes ; microcalorimetry ; NMR ; solvophobic solvation

Sažetak
The solvent influence on the complexation of amphiphilic mannosides, consisting of different non-polar moities, with β-cyclodextrin was explored in a range of temperatures (5 ≤ ϑ/ ºC ≤ 65) by means of microcalorimetry and NMR spectroscopy. The complexation was observed only in strongly hydrogen-bonded solvents (water, formamide, N-methylformamide, and ethylene glycol). The stabilities of complexes were higher in water than in investigated organic solvents, whereby all reactions were enthalpically controlled. A notable temperature dependence of ΔrH○ and ΔrS○ was noticed in water. In contrast, the standard complexation parameters in other investigated solvents exhibited relatively weak temperature dependence. As expected, the complex stability was strongly influenced by compatibilty of the guest and the β-cyclodextrin cavity sizes, as well as the flexibility and structure of the hydrophobic group of investigated mannosides. The carried out investigations provided a deeper insight into the hosting process, demonstrating that solvophobically driven formation of cyclodextrin inclusion complexes is not a water limited phenomenon.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

Napomena
Special Issue of Bulletin of the Chemists and Technologists of Bosnia and Herzegovina

POVEZANOST RADA