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Pregled bibliografske jedinice broj: 954985

The Beneficial Effect of Proanthocyanidins and Icariin on Biochemical Markers of Bone Turnover in Rats

Oršolić, Nada; Nemrava, Johann; Jeleč, Željko; Kukolj, Marina; Odeh, Dyana; Terzić, Svjetlana; Fureš, Rajko; Bagatin, Tomica; Bagatin, Dinko
The Beneficial Effect of Proanthocyanidins and Icariin on Biochemical Markers of Bone Turnover in Rats // International journal of molecular sciences, 19 (2018), 9; 2746, 19 doi:10.3390/ijms19092746 (međunarodna recenzija, članak, znanstveni)

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Naslov
The Beneficial Effect of Proanthocyanidins and Icariin on Biochemical Markers of Bone Turnover in Rats

Autori
Oršolić, Nada ; Nemrava, Johann ; Jeleč, Željko ; Kukolj, Marina ; Odeh, Dyana ; Terzić, Svjetlana ; Fureš, Rajko ; Bagatin, Tomica ; Bagatin, Dinko

Izvornik
International journal of molecular sciences (1422-0067) 19 (2018), 9; 2746, 19

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
proanthocyanidins ; icariin ; retinoic acid-induced bone loss ; rats ; bone markers

Sažetak
Nutrition is an important factor that influences bone metabolism, the endocrine and/or paracrine system, and bone-active mineral elements homeostasis. We studied antiosteoporotic effects of grape seed proanthocyanidins extract, icariin or alendronate (ALN) in retinoic acid-induced (13cRA) bone loss in rats. Proanthocyanidins and icariin have beneficial effects on bone health ; they have improved the bone weight reduction, the length and the diameter of the bone, calcium, and phosphorus content in bone ash, bone mineral density (BMD), the biochemical markers of bone turnover and uterus atrophy induced by 13cRA. All results suggest that proanthocyanidins and icariin reverse osteoporosis in 13cRA rats by stimulating bone formation or regulating bone resorption by their antioxidative and estrogenic-like activity without toxic side-effects observed in ALN treatment.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Farmacija



POVEZANOST RADA

Projekti:
20282313
--IP-2014-09-9730 - Hiperfosforilacija, agregacija i transsinaptički prijenos tau proteina u Alzheimerovoj bolesti: analiza likvora i ispitivanje potencijalnih neuroprotektivnih spojeva (ALZTAUPROTECT) (Šimić, Goran) ( CroRIS)

Ustanove:
Hrvatski veterinarski institut, Zagreb,
Prirodoslovno-matematički fakultet, Zagreb,
Opća bolnica Zabok,
Specijalna bolnica Sv. Katarina

Profili:

Avatar Url Željko Jeleč (autor)

Avatar Url Dyana Odeh (autor)

Avatar Url Tomica Bagatin (autor)

Avatar Url Rajko Fureš (autor)

Avatar Url Svjetlana Terzić (autor)

Avatar Url Dinko Bagatin (autor)

Avatar Url Johann Nemrava (autor)

Avatar Url Marina Kukolj (autor)

Avatar Url Nada Oršolić (autor)

Poveznice na cjeloviti tekst rada:

doi www.mdpi.com

Citiraj ovu publikaciju:

Oršolić, Nada; Nemrava, Johann; Jeleč, Željko; Kukolj, Marina; Odeh, Dyana; Terzić, Svjetlana; Fureš, Rajko; Bagatin, Tomica; Bagatin, Dinko
The Beneficial Effect of Proanthocyanidins and Icariin on Biochemical Markers of Bone Turnover in Rats // International journal of molecular sciences, 19 (2018), 9; 2746, 19 doi:10.3390/ijms19092746 (međunarodna recenzija, članak, znanstveni)
Oršolić, N., Nemrava, J., Jeleč, Ž., Kukolj, M., Odeh, D., Terzić, S., Fureš, R., Bagatin, T. & Bagatin, D. (2018) The Beneficial Effect of Proanthocyanidins and Icariin on Biochemical Markers of Bone Turnover in Rats. International journal of molecular sciences, 19 (9), 2746, 19 doi:10.3390/ijms19092746.
@article{article, author = {Or\v{s}oli\'{c}, Nada and Nemrava, Johann and Jele\v{c}, \v{Z}eljko and Kukolj, Marina and Odeh, Dyana and Terzi\'{c}, Svjetlana and Fure\v{s}, Rajko and Bagatin, Tomica and Bagatin, Dinko}, year = {2018}, pages = {19}, DOI = {10.3390/ijms19092746}, chapter = {2746}, keywords = {proanthocyanidins, icariin, retinoic acid-induced bone loss, rats, bone markers}, journal = {International journal of molecular sciences}, doi = {10.3390/ijms19092746}, volume = {19}, number = {9}, issn = {1422-0067}, title = {The Beneficial Effect of Proanthocyanidins and Icariin on Biochemical Markers of Bone Turnover in Rats}, keyword = {proanthocyanidins, icariin, retinoic acid-induced bone loss, rats, bone markers}, chapternumber = {2746} }
@article{article, author = {Or\v{s}oli\'{c}, Nada and Nemrava, Johann and Jele\v{c}, \v{Z}eljko and Kukolj, Marina and Odeh, Dyana and Terzi\'{c}, Svjetlana and Fure\v{s}, Rajko and Bagatin, Tomica and Bagatin, Dinko}, year = {2018}, pages = {19}, DOI = {10.3390/ijms19092746}, chapter = {2746}, keywords = {proanthocyanidins, icariin, retinoic acid-induced bone loss, rats, bone markers}, journal = {International journal of molecular sciences}, doi = {10.3390/ijms19092746}, volume = {19}, number = {9}, issn = {1422-0067}, title = {The Beneficial Effect of Proanthocyanidins and Icariin on Biochemical Markers of Bone Turnover in Rats}, keyword = {proanthocyanidins, icariin, retinoic acid-induced bone loss, rats, bone markers}, chapternumber = {2746} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE

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