Pregled bibliografske jedinice broj: 949426
Trace N-glycans including sulphated species may originate from various plasma glycoproteins and not necessarily IgG
Trace N-glycans including sulphated species may originate from various plasma glycoproteins and not necessarily IgG // Nature communications, 9 (2018), 1; 2916, 3 doi:10.1038/s41467-018-05173-w (međunarodna recenzija, komentar, znanstveni)
CROSBI ID: 949426 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Trace N-glycans including sulphated species may originate from various plasma glycoproteins and not necessarily IgG
Autori
Lauc, Gordan ; Vučković, Frano ; Bondt, Albert ; Pezer, Marija ; Wuhrer, Manfred
Izvornik
Nature communications (2041-1723) 9
(2018), 1;
2916, 3
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, komentar, znanstveni
Ključne riječi
comment ; N-glycans ; plasma glycoproteins ; IgG
Sažetak
Comment to article entitled “A method to identify trace sulphated IgG N-glycans as biomarkers for rheumatoid arthritis”. The analytical method they used was very sensitive and powerful, providing results for glycans that represented only 0.005% of the glycome. They identified a total of 444 glycan structures and concluded that all these structures are N-glycans that are attached to immunoglobulin G (IgG). However, this glycomic analysis of IgG obtained by protein A purification does not account for the ubiquitous presence of varying levels of other contaminating plasma glycoproteins.
Izvorni jezik
Engleski
Znanstvena područja
Biologija
POVEZANOST RADA
Ustanove:
Farmaceutsko-biokemijski fakultet, Zagreb,
GENOS d.o.o.
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
- Nature Index
