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Pregled bibliografske jedinice broj: 938500

Cell penetrating, mitochondria targeting multiply charged DABCO-cyanine dyes


Kurutos, Atanas; Orehovec, Iva; Saftić, Dijana; Horvat, Lucija; Crnolatac, Ivo; Piantanida, Ivo; Deligeorgiev, Todor
Cell penetrating, mitochondria targeting multiply charged DABCO-cyanine dyes // Dyes and pigments, 158 (2018), 517-525 doi:10.1016/j.dyepig.2018.05.035 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 938500 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Cell penetrating, mitochondria targeting multiply charged DABCO-cyanine dyes

Autori
Kurutos, Atanas ; Orehovec, Iva ; Saftić, Dijana ; Horvat, Lucija ; Crnolatac, Ivo ; Piantanida, Ivo ; Deligeorgiev, Todor

Izvornik
Dyes and pigments (0143-7208) 158 (2018); 517-525

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
cyanine ; DABCO ; mitochondria ; fluorescence ; confocal microscopy

Sažetak
We have prepared new series of lipophilic cyanine dyes equipped with several cationic quaternary ammonium moieties. This was achieved by introducing DABCO within the structures. Furthermore, to investigate the influence of the additional cationic charges to the mitochondrial uptake, DABCO was quaternized with methyl group or alkyl piperidine cation. Spectroscopic and isothermal titration calorimetry studies as well as MTT assay and subcellular localization using confocal laser scanning microscopy revealed the presented dyes combine very low cytotoxicity with efficient cellular uptake and remarkable fluorescent marking of mitochondria.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje)



POVEZANOST RADA


Projekti:
HRZZ-IP-2013-11-1477 - Višenamjensko očitavanje DNA/RNA sekundarne strukture molekularnim kemijskim senzorima (DNA/RNA-MolSense) (Piantanida, Ivo, HRZZ - 2013-11) ( CroRIS)

Ustanove:
Institut "Ruđer Bošković", Zagreb

Poveznice na cjeloviti tekst rada:

doi www.sciencedirect.com

Citiraj ovu publikaciju:

Kurutos, Atanas; Orehovec, Iva; Saftić, Dijana; Horvat, Lucija; Crnolatac, Ivo; Piantanida, Ivo; Deligeorgiev, Todor
Cell penetrating, mitochondria targeting multiply charged DABCO-cyanine dyes // Dyes and pigments, 158 (2018), 517-525 doi:10.1016/j.dyepig.2018.05.035 (međunarodna recenzija, članak, znanstveni)
Kurutos, A., Orehovec, I., Saftić, D., Horvat, L., Crnolatac, I., Piantanida, I. & Deligeorgiev, T. (2018) Cell penetrating, mitochondria targeting multiply charged DABCO-cyanine dyes. Dyes and pigments, 158, 517-525 doi:10.1016/j.dyepig.2018.05.035.
@article{article, author = {Kurutos, Atanas and Orehovec, Iva and Safti\'{c}, Dijana and Horvat, Lucija and Crnolatac, Ivo and Piantanida, Ivo and Deligeorgiev, Todor}, year = {2018}, pages = {517-525}, DOI = {10.1016/j.dyepig.2018.05.035}, keywords = {cyanine, DABCO, mitochondria, fluorescence, confocal microscopy}, journal = {Dyes and pigments}, doi = {10.1016/j.dyepig.2018.05.035}, volume = {158}, issn = {0143-7208}, title = {Cell penetrating, mitochondria targeting multiply charged DABCO-cyanine dyes}, keyword = {cyanine, DABCO, mitochondria, fluorescence, confocal microscopy} }
@article{article, author = {Kurutos, Atanas and Orehovec, Iva and Safti\'{c}, Dijana and Horvat, Lucija and Crnolatac, Ivo and Piantanida, Ivo and Deligeorgiev, Todor}, year = {2018}, pages = {517-525}, DOI = {10.1016/j.dyepig.2018.05.035}, keywords = {cyanine, DABCO, mitochondria, fluorescence, confocal microscopy}, journal = {Dyes and pigments}, doi = {10.1016/j.dyepig.2018.05.035}, volume = {158}, issn = {0143-7208}, title = {Cell penetrating, mitochondria targeting multiply charged DABCO-cyanine dyes}, keyword = {cyanine, DABCO, mitochondria, fluorescence, confocal microscopy} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus


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