Naslov
Heavy rare earth elements affect Sphaerechinus granularis sea urchin early life stages by multiple toxicity endpoints

Autori
Gravina, Maria ; Pagano, Giovanni ; Oral, Rahime ; Guida, Marco ; Toscanesi, Maria ; Siciliano, Antonietta ; Di Nunzio, Aldo ; Burić, Petra ; Lyons, Daniel Mark ; Thomas, Philippe J. ; Trifuoggi, Marco

Izvornik
Bulletin of environmental contamination and toxicology (0007-4861) 100 (2018), 5; 641-646

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Heavy rare earth elements ; Sea urchins ; Embryotoxicity ; Spermiotoxicity ; Cytogenetic damage

Sažetak
Heavy rare earth elements (HREEs) were tested for adverse effects to early life stages of the sea urchin Sphaerechinus granularis. Embryos were exposed to analytically measured HREE concentrations ranging from 10-7 to 10-5 M. No significant developmental defects (DD) increases were observed in embryos exposed to 10-7 M HREEs, whereas 10-5 M HREEs resulted in significant DD increase up to 96% for HoCl3 vs. 14% in controls. Embryos exposed to 10-6 M HREEs showed the highest DD frequency in embryos exposed to 10-6 M DyCl3 and HoCl3. Cytogenetic analysis of HREE-exposed embryos revealed a significant decrease in mitotic activity, with increases in mitotic aberrations. When S. granularis sperm were exposed to HREEs, a significant decrease of fertilization success was observed, with the offspring of sperm exposed to 10-5 M GdCl3 and LuCl3 showing significant DD increases. The results warrant investigations on HREEs in other test systems, and on REE-containing complex mixtures.

Izvorni jezik
Engleski

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