Naslov
Quantification of dioxins and furan in sediments and water

Autori
Mandić Andačić, Ivana ; Palac Bešlić, Iva ; Petrović, Marinko ; Tolić, Sonja ; Šikić, Sandra ; Žuntar, Irena ; Krivohlavek, Adela

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo

Izvornik
The 5th Croatian Congress of Toxicology with International Participation (CROTOX 2016) : Abstracts ; u: Archives of Industrial Hygiene and Toxicology 67 (2016) (S) / Durgo, Ksenija - Zagreb : Institut za medicinska istraživanja i medicinu rada, 2016, 55-55

Skup
Croatian Congress of Toxicology with International Participation (2016 ; 5)

Mjesto i datum
Poreč, Hrvatska, 09.10.2016. - 12.10.2016

Vrsta sudjelovanja
Poster

Vrsta recenzije
Recenziran

Ključne riječi
GC-MS/MS, PCDDs, PCDFs, Teaching Institute, TEF value

Sažetak
The group of Polychlorinated Dibenzo-p-dioxins (PCDDs, Dioxins) and Polychlorinated Dibenzofurans (PCDFs, Furans) consists of 210 organic compounds (congeners), whichdiffer widely in their chlorine content and respective toxicities. In particular, 17 of these are extremely toxic. The most well-known compound is 2, 3, 7, 8 tetrachloro-dibenzo-p-dioxin (2, 3, 7, 8 –TCDD). The toxicity of dioxins and furans is calculated usingthe toxicity equivalence factor (TEF) specified by the World Health Organization (WHO). According to WHO, the TEF value for 2, 3, 7, 8 TCDD is one. PCDDs and PCDFs have shown toxic effects in animal studies ; they damage reproductive and immune systems and are also carcinogenic. Dioxins are mainly formed as an unwanted by-product in combustion processes in case of which traces of chlorine can be found as by-products of the combustion of contaminated chemical waste, chemical and pesticide manufacturing, pulp and paper bleaching processes, and other sources. These compounds are extremely stable, both in terms of their chemical and thermal qualities, and persist in the environment for many years. In the Teaching Institute of Public Health ''Dr. Andrija Štampar'', the gas chromatography coupled to triple quadrupole mass spectrometry (GC-MS/MS) method for determination of PCDDs and PCDFs is used. Until now, 135 water and 28 sediment samples were analysed. For all samples the results were below the limit of quantitation. Due to the environmental stability of PCDDs and PCDFs and their harmful effects on human health it is necessary to carry out continuous control for public health purposes.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

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