Naslov
Radiological and Necropsy Findings in Dogs with Leptospirosis Pulmonary Haemorrhagic Syndrome

Autori
Habuš, Josipa ; Gudan, Andrea ; Škrlin, Branimi ; Štritof, Zrinka ; Mojčec Perko, Vesna ; Hađina, Suzana ; Stevanović, Vladimir ; Perharić, Matko ; Martinković, Krešimir ; Huber Doroteja ; Milas, Zoran ; Turk, Nenad

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo

Izvornik
10th International Leptospirosis Society Conference 2017 "Science for People" / - Palmerston North, 2017, 236-236

Skup
10th International Leptospirosis Society Conference 2017 "Science for People"

Mjesto i datum
Palmerston North, Novi Zeland, 27.11.2017. - 01.12.2017

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
dogs, leptospirosis, LPHS

Sažetak
Background: Severe manifestations of leptospirosis in dogs are usually associated with icterus, impaired renal and/or hepatic function and haemorrhage. Pulmonary involvement, in a form of leptospirosis pulmonary haemorrhagic syndrome (LPHS), is less known but an emerging problem (Klopfleisch 2010). Objective of this work was to describe radiological and necropsy findings of 14 dogs with confirmed LPHS. Methods: Laboratory diagnosis of leptospirosis was based on Microscopic agglutination test (cut off titre of ≥ 1:800), positive blood polymerase chain reaction or isolation of Leptospira spp. from the blood or urine. Thoracic radiographs and necropsy findings of dogs with confirmed LPHS were reviewed and compared. Results: Serogroup Pomona was identified in 7 of 11 cases in which determination of presumptive infective serovar was feasible. Radiological findings revealed reticulonodular pulmonary opacities In 11 dogs. In four dogs the entire lung was affected, while in seven dogs reticulonodular patterns were observed predominantly in the caudodorsal lung field. In three dogs thoracic radiographs showed no signs of hemorrhage. Necropsy revealed severe and diffuse pulmonary haemorrhage affecting all lung lobes in all 14 animals. Histological evidence of alveolar haemorrhage, alveolar hyaline membranes, mild alveolar wall necrosis and scant infiltrates of neutrophils (mostly perivascular) was detected. Conclusions: In Croatia, most of the LPHS cases in dogs were caused by serogroup Pomona. Despite the fact that necropsy findings in all cases revealed extensive pulmonary haemorrhage, radiological pulmonary changes were not always seen on the initial or even on the repeated radiographs. Results of this study indicate that dogs with leptospirosis should be closely monitored as pulmonary haemorrhage may occur and progress very rapidly.

Izvorni jezik
Engleski

Znanstvena područja
Veterinarska medicina

POVEZANOST RADA