Naslov
Microbiota plays a role in oral immune priming in Tribolium castaneum

Autori
Futo, Momir ; Kurtz, Joachim

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Skup
15th Congress of The European Society for Evolutionary Biology

Mjesto i datum
Lausanne, Švicarska, 10.08.2015. - 14.08.2015

Vrsta sudjelovanja
Poster

Vrsta recenzije
Podatak o recenziji nije dostupan

Ključne riječi
microbiota, oral immune priming, Tribolium castaneum

Sažetak
Animals are inhabited by a diverse community of microorganisms. The relevance of such microbiota is increasingly being recognised in a broad spectrum of species, ranging from sponges to primates, revealing various beneficial roles microbes can play. The red flour beetle Tribolium castaneum represents a well-established experimental model organism for studying questions in ecology and evolution, however, the relevance of its microbial community is still largely unknown. T. castaneum larvae orally exposed to inactivated bacterial components of the entomopathogen Bacillus thuringiensis tenebrionis showed increased survival upon a subsequent challenge with this bacterium. We explored the role of microbiota for oral immune priming in this species. To investigate whether T. castaneum microbiota plays a role in this phenomenon, we established a protocol for raising germ-free larvae and subsequently tested whether they differ in their ability to mount such a priming response. Here we demonstrate that larvae, which lack their microbiota, show decreased survival upon secondary challenge with bacterial spores, compared to animals which still had, or were allowed to regain their microbiota before priming. Although the exact mechanism of oral immune priming is still unclear, we here suggest that the microbiota plays a crucial role in oral immune priming in this species.

Izvorni jezik
Engleski

Znanstvena područja
Biologija

POVEZANOST RADA