Naslov
Viscoelastic behavior of mineralized (CaCO3) chitin based PVP-CMC hydrogel scaffolds

Autori
Čadež, Vida ; Saha, Nabanita ; Dutour Sikirić, Maja ; Saha, Petr

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
AIP Conference Proceedings / Zatloukal, Martin - Online : American Institute of Physics (AIP), 2017

ISBN
978-0-7354-1513-3

Skup
Novel trends in rheology VII

Mjesto i datum
Zlín, Češka Republika, 26.07.2017. - 27.07.2017

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
hydrogels ; viscosity ; biodegradation ; viscoelasticity ; elastic moduli

Sažetak
Enhancement of the mechanical as well as functional properties of the perspective mineralized PVP-CMC-CaCO3 hydrogel scaffold applicable for bone tissue engineering is quite essential. Therefore, the incorporation feasibility of chitin, a bioactive, antibacterial and biodegradable material, was examined in order to test its ability to enchance mechanical properties of the PVP-CMC- CaCO3 hydrogel scaffold. Chitin based PVP-CMC hydrogels were prepared and characterized both as non-mineralized and mineralized (CaCO3) form of hydrogel scaffolds. Both α-chitin (commercially bought) and β-chitin (isolated from the cuttlebone) were individually tested. It was observed that at 1% strain all hydrogel scaffolds have linear trend, with highly pronounced elastic properties in comparison to viscous ones. The complex viscosity has directly proportional behavior with negative slope against angular frequency within the range of ω = 0.1 − 100 rad.s−1. Incorporation of β-chitin increased storage modulus of all mineralized samples, making it interesting for further research.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje)

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