Naslov
Comparative analysis op electroencephalographic abnormalities in aseptic nonherpetic meningitis and migraine

Autori
Petković, Dobrinka ; Vuković, Borislav ; Andrić, Zdravko

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, prošireni sažetak, znanstveni

Izvornik
Periodicum Biologorum / - , 2013, 78-78

Skup
53rd International Neuropsychiatric Congress Pula

Mjesto i datum
Pula, Hrvatska, 19.06.2013. - 22.06.2013

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
aseptic nonherpetic meningitis ; migraine without aura ; EEG

Sažetak
Introduction: Viral nonherpetic meningitis is mostly caused by around 30 types of nonpolioenteroviruses. Electroencephalographic record in inflammatory CNS diseases characterises the loss of alpha rhytm and appearance of theta waves. EEG abnormalities occur by nonneurotropical viral infections of CNS without clinical signs of encephalitis, so that in aseptical nonherpetic meningitis often detect nonspecific diffuse or focal EEG abnormalities. Similar paralogical EEG registrated in same patients with migraine . Objectives: Comparison of patients with aseptic meningitis with paralogical and normal EEG, according to age, sex, duration of symptoms and cerebrospinal fluid results. Definition frequencies of electroencephalographic abnormalities in aseptic meningitis towards migraines without aura group patients. Comparison of EEG abnormalities in patients with migraine according to age and sex. Methods: Adults patients with aseptic meningitis in acute phase disease which was confirmed by liquor examination were investigation . Migraine without aura group contains adults without evidence of meningeal inflammation, epilepsy, previous head trauma, psychiatric or neurologic disease. EEG recordings were evaluated according to standards for age. Statistical method: x2 test, p < 0, 05 Results: The study included 51 patients with aseptic meningitis, female 50, 9%, male 49%, aged 18 — 60. Paralogical EEG: 35 patients 68, 62%, female 41, 17% , male 27, 4% ( diffuse abnormalities 40%, focal 60%). Duration of the symptoms: 7—14 days Examination of the CFS: range of the cell count/mm3: 6-. 2560, X± SD 375, 21±530, 48 ; level of protein: range 0, 20-1, 22 g/L The study included 55 patients with migraine without aura (female 78, 18%, male 21, 81 % ), aged 21-68, X± SD 40, 34± 11, 39 Pathological EEG: 20 patients 36, 36% (female 23, 63 %, male 12, 72% ) Conclusion: 51 adult patients with aseptic nonherpetic meningitis were treated at the County Hospital Pozega, Department of Infectology. Pathological electroencephalographic record confirmed 68, 62 % of the patients with clear mental status and absence of focal neurological signs which indicates the progress an infectious encephalopathy, clinically silent parenchy- mal inflammation remains questionable. Statistically significant difference in patients with aseptic meningitis with pathological and normal EEG according to sex (p = 0.50), age (p = 0, 259), duration of symptoms (p =0, 471), CSF cell count (p = 0, 380) and level of protein (p = 0, 542) wasn’1 confirmed. In 55 cases of migraines without aura, pathological EEG was detected in 36, 33 %, without statistically significant difference between patients widi pathological and normal EEG to age (p=0, i486) and sex (p=0, 073). Significantly more patients with aseptic meningitis had pathological electroencephalographic than patients with migraine (p=0.002).

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA