Naslov
Microscopy in Urolithiasis Research

Autori
Vesna, Babić-Ivančić ; Maja, Dutour Sikirić ; Anamarija, Stanković ; Silvija, Šafranko

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
13th Multinational Congress on Microscopy / Gajović, Andreja ; Weber, Igor ; Kovačević, Goran ; Čadež, Vida ; Šegota, Suzana ; Vidoš, Ana - Zagreb : Institut Ruđer Bošković ; Hrvatsko mikroskopijsko društvo, 2017, 472-472

ISBN
978-953-7941-19-2

Skup
13th Multinational Congress on Microscopy

Mjesto i datum
Rovinj, Hrvatska, 24.09.2017. - 29.09.2017

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
urolithiasis, microscopy, crystals, calcium oxalate

Sažetak
The crystallization is process of the formation a crystalline phase from a parent phase, e.g. solution. The normal (bone, teeth, shells) and pathological mineralized tissues (stones, caries, gouty arthritis, arteriosclerosis) are biominerals in human body and animals. The formation of biominerals, is the formation of sparingly soluble salts from body fluids (blood, serum, urine) within an organic macromolecular matrix. Processes involved in pathological mineralization are of special interest due to the great medical and social problems that they cause. Urolithiasis, a form of pathologic biomineralization, is a disease which causes the formation of urinary stones in different parts of kidney or bladder (1). The kidney stones formation under biological conditions can be triggered by various metabolic disorders such as: hipercalciuria, hypocitraturia, hiperoxaluria and the change in the urine acidity. The mechanisms and the conditions under which they crystallize are still not completely clarified. In this work, the crystallization from supersaturated solution in model system, calcium oxalates, calcium phosphates, magnesium phosphates, uric acid and/or salts of the uric acid, also in artificial urine were reported. The reactant solutions were mixed under controlled hydrodynamic and thermodynamic conditions ; pH, ionic strength, temperature. The influence of aditives, macromolecules on crystal growth morphology and on the composition of the crystallizing phase were determined. The crystalluria from real urine system as one indicator the formation of calculi were compared with the morphology and composition of crystals which crystalized in model systems. The changes in the composition and morphology of precipitated salts were observed by means of PXRD, light microscopy, TEM, SEM, IR and TGA.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

POVEZANOST RADA