Naslov
Mapping of heterozygosity rich regions in Austrian pinzgauer cattle

Autori
Ferenčaković, Maja ; Banadinović, Maja ; Mercvajler, Mario ; Khayatzadeh, Negar ; Cubric Curik, Vlatka ; Curik, Ino ; Sölkner, Johann ; Mészáros, Gábor

Izvornik
Acta agriculturae Slovenica (1581-9175) 5 (2016); 41-44

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
cattle ; Pinzgauer ; heterozygosity rich regions ; SNP data

Sažetak
Heterozygosity, the state of possessing di erent alleles at a given locus of an individual, is functionally related to inbreeding, heterosis and biodiversity. We questioned the appearance of regions with extraordinary high rates of het- erozygosity, here “Heterozygosity Rich Regions” (HRR) in the genomes of a cattle population. We used 120 Pinzgauer bulls genotyped with 611102 SNPs and detected 14702 HRR unequally dispersed in the genome. Mean coverage of SNP chip data with HRR was 0.99 %. In total we found 11 regions with high frequency of SNPs being in HRR on nine chromosomes yielding 21 genes of which 17 have described functions. We further identi ed genes located in HRR and discussed their importance and function. e results of this study point to the analysis of HRR providing additional understanding of the genomes of livestock.

Izvorni jezik
Engleski

Znanstvena područja
Poljoprivreda (agronomija), Biotehnologija

POVEZANOST RADA