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Pregled bibliografske jedinice broj: 888644

An elution mobile phase and process for immunoaffinity chromatography of viruses


Brgles, Marija; Halassy, Beata; Forčić, Dubravko
An elution mobile phase and process for immunoaffinity chromatography of viruses
Hrvatski patentni glasnik 16 (2017) 1.


CROSBI ID: 888644 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
An elution mobile phase and process for immunoaffinity chromatography of viruses

Autori
Brgles, Marija ; Halassy, Beata ; Forčić, Dubravko

Broj patenta
WO 2017/129450 A1

Godina
2017

Nositelj prava
Sveučilište u Zagrebu, Zagreb, Hrvatska

Sažetak
The present invention discloses a novel composition of the elution mobile phase for virus purification by immunoaffinity chromatography which consists of one or more amino acids: L-serine, L-asparagine, or L- glutamine, or their salts with pharmaceutically acceptable acids ; one or more auxiliary ingredients: L-arginine, glycine or imidazole, or their salts with pharmaceutically acceptable acids ; one or more pharmaceutically acceptable pH adjusting agents for correcting the pH value of the mobile phase from pH = 6.0 - 8.0 ; and purified water, up to 100 % w/w of the mobile phase composition. The invention provides the use of immunoaffinity chromatography as a key step in the production of viral vaccines and/or viral vectors, in separation of infectious from non-infectious viral particles, and for enrichment of the viral suspension in infectious viral particles.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Biotehnologija



POVEZANOST RADA


Projekti:
HRZZ-UIP-2013-11-8193 - Kromatografsko pročišćavanje biomolekula i njihova karakterizacija (CHROBIO) (Brgles, Marija, HRZZ - 2013-11) ( CroRIS)

Ustanove:
Sveučilište u Zagrebu

Profili:

Avatar Url Beata Halassy (autor)

Avatar Url Marija Brgles (autor)

Avatar Url Dubravko Forčić (autor)


Citiraj ovu publikaciju:

Brgles, Marija; Halassy, Beata; Forčić, Dubravko
An elution mobile phase and process for immunoaffinity chromatography of viruses
Hrvatski patentni glasnik 16 (2017) 1.
Sveučilište u Zagrebu (2017) An elution mobile phase and process for immunoaffinity chromatography of viruses, WO 2017/129450 A1.
@patent{patent, author = {Brgles, Marija and Halassy, Beata and For\v{c}i\'{c}, Dubravko}, year = {2017}, keywords = {}, title = {An elution mobile phase and process for immunoaffinity chromatography of viruses}, keyword = {}, publisherplace = {Zagreb} }
@patent{patent, author = {Brgles, Marija and Halassy, Beata and For\v{c}i\'{c}, Dubravko}, year = {2017}, keywords = {}, title = {An elution mobile phase and process for immunoaffinity chromatography of viruses}, keyword = {}, publisherplace = {Zagreb} }




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